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Immunomodulatory effect of S. thermophilus : An experimental study

Keywords: Immune response (IR) , Immunological tests , Probiotics , S.Thermophillus

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Abstract:

The most promising development in the area of functional foods has been the use of probiotics & their role in human health and disease. Much of the research work in probiotics has been focused on the gastrointestinal tract. One of these putative effects is the alteration of immune function. Studies reveal that the probiotics have a positive effect on the gut immunity. But hardly any work has been carried out on the effect of probiotics on the systemic immunity. Moreover this effect varies with not only the genera andspecies of the probiotic but also with type of probiotic. It has been shown in the literature that only the live probiotics are capable of showing an effect. In the present study experiments were carried out to see the effect of probiotics Streptococcus thermophilus (S. thermophilus) both live and dead on systemicimmune response. Results reveal that S.thermophilus feeding, both in dead and alive form, could modify both the humoral and cellmediated immune response, however, the effect was more pronounced with the live form.”

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