Precursor cells in the hematopoietic stromal microenvironment

The manuscript summarizes the works of Prof. Joseph Chertkov that are dedicated to precursor cells in the hematopoietic stromal microenvironment. Unique functional analysis was used in these investigations. The properties of stem cells in the hematopoietic microenvironment such as self-renewal capacity and the ability to differentiate into all stromal lineages are described. The hierarchical structure of stromal precursor cells compartment is proposed. Some elements of the regulatory pathways of stromal precursor cells are described. This compilation reflects the importance of Prof. Chertkov’s contribution to the investigation of stromal precursor cells and hematopoiesis.