A.J. Friedenstein, founder of the mesenchymal stem cell concept

The outstanding scientists A. Maximow and A. Friedenstein consecrated their lives to the study of stem cells. A. Maximow created a theory of hematopoiesis and a concept of hematopoietic stem cells, A. Friedenstein discovered mesenchymal stem cells and the hematopoietic microenvironment. The achievement of both researchers inspired other scientists and doctors to develop hematopoietic stem cell transplantation and other methods of cellular therapy as a treatment for a variety of severe diseases.