We sought to develop and deploy a video-based smartphone-delivered mobile HIV Risk Reduction (mHIVRR) intervention to individuals in an addiction treatment clinic. We developed 3 video modules that consisted of a 10-minute HIVRR video, 11 acceptability questions, and 3 knowledge questions and deployed them as a secondary study within a larger study of ecological momentary and geographical momentary assessments. All 24 individuals who remained in the main study long enough completed the mHIVRR secondary study. All 3 videos met our a priori criteria for acceptability “as is” in the population: they achieved median scores of ≤2.5 on a 5-point Likert scale; ≤20% of the individuals gave them the most negative rating on the scale; a majority of the individuals stated that they would not prefer other formats over video-based smartphone-delivered one (all ). Additionally, all of our video modules met our a priori criteria for feasibility: ≤20% of data were missing due to participant noncompliance and ≤20% were missing due to technical failure. We concluded that video-based mHIVRR education delivered via smartphone is acceptable, feasible and may increase HIV/STD risk reduction knowledge. Future studies, with pre-intervention assessments of knowledge and random assignment, are needed to confirm these findings. 1. Introduction The use of mobile and desktop computer technologies in HIV healthcare and prevention delivery has been on the rise using a variety of technology platforms, including desktop computers [1–4], web-based systems [5–8], social networking sites, interactive voice response [9], personal digital assistants (PDAs)/smartphones, and short message service (SMS)/text messaging [10–13]. The range of indications for these electronic interventions is even broader than the range of technologies used; electronic interventions have been explored for HIV prevention [2], self-efficacy enhancement [14], antiretroviral therapy adherence [7], social support, appropriate care referrals [1], and internet health literacy [15]. The interest in electronic technology in healthcare delivery derives in large part from its potential to increase access to care in a cost-effective manner, especially for people who are underserved due to poverty, rural residence, unforgiving schedules, or other barriers to regular office visits. There is growing evidence that mobile health technologies can be effectively utilized in resource-limited settings in both the developed and developing world. For example, Muessig et al. [16] found that for young black men who have sex with men (MSM)
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