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Anemia  2013 

Rapid Assessment for Coexistence of Vitamin B12 and Iron Deficiency Anemia among Adolescent Males and Females in Northern Himalayan State of India

DOI: 10.1155/2013/959605

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Abstract:

Coexistence of folic acid and vitamin B12 deficiency has been observed among adolescents with iron deficiency anemia, but limited evidence is available from India. So, a rapid assessment was done to study the prevalence of iron, folic acid, and vitamin B12 deficiency among adolescent males and females in northern Himalayan state in India. Methods. Total 885 (female: 60.9%) adolescents (11 to 19 completed years) were surveyed from 30-cluster village from two community development blocks of Himachal Pradesh. Serum ferritin, folic acid, and vitamin B12 were estimated among randomly selected 100 male and 100 female adolescents. Results. Under-nutrition (BMI < 18.5?kg/m2) was observed among 68.9% of adolescents (male: 67.1%; female: 70.7; ). Anemia was observed to be prevalent among 87.2% males and 96.7% females ( ). Mild form of anemia was observed to be the most common (53.9%) form followed by moderate (29.7%) anemia. Strikingly, it was found that all the adolescents were deficient in vitamin B12 and none of the adolescents was observed to be deficient in folic acid. Conclusion. Among both male and female adolescents anemia with vitamin B12 deficiency was observed to be a significant public health problem. Folic acid deficiency was not observed as a problem among surveyed adolescents. 1. Introduction Iron deficiency anemia is still a condition of a major public health concern for researchers and policy makers [1]. Period of adolescence is a significant phase of life as the physiologic growth spurt requires adequate nutrition in order to achieve healthy adulthood. Iron deficiency anemia reflects the state of undernutrition among adolescents. It results due to inadequate nutrition, blood loss, and inflammatory and infectious diseases. Iron deficiency anemia occurs because of poor intake and absorption is the most common form of anemia [2]. In India, the prevalence of iron deficiency anemia had been reported to be 55.8% among females and 30.2% among males in age group of 15–19 years [3]. Adolescent girls of 11–19 years across 16 districts observed the prevalence of anemia to be 90.0%, which was significantly more as compared to national level survey [4]. Iron requires haemglobin (Hb) synthesis in red blood cells and low level of Hb clinically determines anemia. In addition to iron, the haematopoiesis requires sufficient amount of other nutrients, like folic acid and vitamin B12 require red blood cells production [5]. Folic acid is a water soluble vitamin involved in nucleic acid, blood cell, and nervous tissue synthesis. It is widely distributed in green

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