Socioeconomic Assessment and Impact of Social Security on Outcome in Patients Admitted with Suspected Coronary Chest Pain in the City of Salta, Argentina
Low socioeconomic status is associated with increased mortality from coronary heart disease. We assessed total mortality, cardiac death, and sudden cardiac death (SCD) in relation to socioeconomic class and social security in 982 patients consecutively admitted with suspected coronary chest pain, living in the city of Salta, northern Argentina. Patients were divided into three socioeconomic classes based on monthly income, residential area, and insurance coverage. Five-year follow-up data were analyzed accordingly, applying univariate and multivariate analyses. At follow-up, 173 patients (17.6%) had died. In 92 patients (9.4%) death was defined as cardiac, of whom 59 patients (6.0%) were characterized as SCD. In the multivariate analysis, the hazard ratios (HRs) for all-cause and cardiac mortality in the highest as compared to the lowest socioeconomic class were 0.42 (95% confidence interval (CI), 0.22–0.80), , and 0.39 (95% CI, 0.15–0.99), , respectively. Comparing patients in the upper socioeconomic class to patients without healthcare coverage, HRs were 0.46 (95% CI, 0.23–0.94), , and 0.37 (95% CI, 0.14–1.01), , respectively. In conclusion, survival was mainly tied to socioeconomic inequalities in this population, and the impact of a social security program needs further attention. 1. Introduction In addition to the well-known risk factors for cardiovascular disease, such as hypertension, diabetes, cigarette smoking, hypercholesterolemia, obesity, and a sedentary lifestyle [1], socioeconomic status may also have an impact on prognosis [2]. As socioeconomic inequalities vary between countries and regions, they need to be accounted for in risk assessment within communities with marked social gradients. To our knowledge, socioeconomic inequalities and their associations with cardiovascular mortality have not been studied in Salta, northern Argentina. According to official data [3] 7.9% of the population in the Salta region is unemployed, but a wider definition than the one used would indicate an incidence of 29.3% (local data attached to the official data), and 60% are without a health security program (Table 1) [3]. Table 1: General demographic indicators in Argentinean and Salta populations [ 3]. The city of Salta has two large public hospitals, one for adults (405 beds) and one for obstetrics and pediatrics. They provide comprehensive care for patients in all medical and surgical specialties, but high-cost medical treatment is not widely available in the province of Salta. In the city of Salta there are also eleven private clinics with a total number
References
[1]
G. A. Kaplan and J. E. Keil, “Socioeconomic factors and cardiovascular disease: a review of the literature,” Circulation, vol. 88, no. 4 I, pp. 1973–1998, 1993.
[2]
L. J. Waite, Ed., Aging, Health, and Public Policy: Demographic and Economic Perspectives, vol. 30 of Population and Development Review Supplement, Population Council, New York, NY, USA, 2004.
[3]
Health minister of Argentina, “National department of statistical and health information,” 2011, http://www.deis.gov.ar/.
[4]
R. León de la Fuente, P. A. Naesgaard, S. T. Nilsen et al., “B-type natriuretic peptide and high sensitive C-reactive protein predict 2-year all cause mortality in chest pain patients: a prospective observational study from Salta, Argentina,” BMC Cardiovascular Disorders, vol. 11, article 57, 2011.
[5]
P. A. Naesgaard, R. A. León de la Fuente, S. T. Nilsen et al., “Serum 25(OH)D is a 2-year predictor of all-cause mortality, cardiac death and sudden cardiac death in chest pain patients from Northern Argentina,” PLoS ONE, vol. 7, no. 9, Article ID e43228, 2012.
[6]
“Indicadores bàsicos 2012,” Ministerio de Salud, Presidencia de la Nación, Organización Panamericana de la Salud.
[7]
T. Killip III and J. T. Kimball, “Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients,” The American Journal of Cardiology, vol. 20, no. 4, pp. 457–464, 1967.
[8]
J. W. Lynch, G. A. Kaplan, R. D. Cohen, J. Tuomilehto, and J. T. Salonen, “Do cardiovascular risk factors explain the relation between socioeconomic status, risk of all-cause mortality, cardiovascular mortality, and acute myocardial infarction?” The American Journal of Epidemiology, vol. 144, no. 10, pp. 934–942, 1996.
[9]
I. Holme, A. Helgeland, and I. Hjermann, “Four-year mortality by some socioeconomic indicators: the Oslo study,” Journal of Epidemiology and Community Health, vol. 34, no. 1, pp. 48–52, 1980.
[10]
K. Reinier, E. Thomas, D. L. Andrusiek et al., “Socioeconomic status and incidence of sudden cardiac arrest,” Canadian Medical Association Journal, vol. 183, no. 15, pp. 1705–1712, 2011.
[11]
K. Reinier, E. C. Stecker, C. Vickers, K. Gunson, J. Jui, and S. S. Chugh, “Incidence of sudden cardiac arrest is higher in areas of low socioeconomic status: a prospective two year study in a large United States community,” Resuscitation, vol. 70, no. 2, pp. 186–192, 2006.
[12]
J. P. Mackenbach, A. E. Cavelaars, A. E. Kunst, and F. Groenhof, “Socioeconomic inequalities in cardiovascular disease mortality; an international study,” European Heart Journal, vol. 21, no. 14, pp. 1141–1151, 2000.
[13]
P. Suadicani, A. O. Hein, and F. Gyntelberg, “Strong Mediators of social inequalities in risk of ischaemic heart disease: a six years follow-up in the Copenhagen male study,” Interventional Journal of Epidemiology, vol. 26, no. 3, pp. 515–522, 1997.
[14]
M. Woodward, M. C. Shewry, W. C. S. Smith, and H. Tunstall-Pedoe, “Social status and coronary heart disease: results from the Scottish heart health study,” Preventive Medicine, vol. 21, no. 1, pp. 136–148, 1992.
[15]
H. Tunstall-Pedoe, M. Woodward, R. Tavendale, R. A'Brook, and M. K. McCluskey, “Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish heart health study: cohort study,” The British Medical Journal, vol. 315, no. 7110, pp. 722–729, 1997.
[16]
M. Woodward, J. Oliphant, G. Lowe, and H. Tunstall-Pedoe, “Contribution of contemporaneous risk factors to social inequality in coronary heart disease and all causes mortality,” Preventive Medicine, vol. 36, no. 5, pp. 561–568, 2003.
[17]
J. P. Mackenbach, I. Stirbu, A. J. R. Roskam et al., “Socioeconomic inequalities in health in 22 European countries,” The New England Journal of Medicine, vol. 358, no. 23, pp. 2468–2481, 2008.
[18]
K. Liu, L. B. Cedres, J. Stamler et al., “Relationship of education to major risk factors and death from coronary heart disease, cardiovascular diseases and all causes. Findings of three Chicago epidemiological studies,” Circulation, vol. 66, no. 6 I, pp. 1308–1314, 1982.
[19]
L. H. Ishitani, G. C. Franco, I. H. Perpétuo, and E. Fran?a, “Socioeconomic inequalities and premature mortality due to cardiovascular diseases in Brazil,” Revista de Saúde Pública, vol. 40, no. 4, pp. 684–691, 2006.