Background. Laparoscopic Roux-en-Y gastric bypass (LRYGB) is one of the most widely used bariatric procedures today, and laparoscopic sleeve gastrectomy (LSG) as a single-stage procedure for the treatment of morbid obesity is becoming increasingly popular in Europe. The aim of this study was to compare short- and midterm results between LRYGB and LSG. Methods. An observational retrospective study from a database of patients undergoing LRYGB and LSG between January 2008 and June 2011. Seventy patients (mean age 39 years) were included. Patients were followed at 6, 12, and 18 months. Operative time, length of stay, weight loss, comorbidity improvement or resolution, postoperative complications, reinterventions and mortality were evaluated. Results. Thirty-six LRYGB and 34 LSG were included. Mean operative time of LSG was 106？min while LRYGB was 196？min ( ). Differences in length of stay, early and late complications, and improvement or resolution in comorbidities were not significant ( ). Eighteen months after surgery, average excess weight loss was 77.6% in LRYGB and 57.1% in LSG ( ). There was no surgery-related mortality. Conclusions. Both LRYGB and LSG are safe procedures that provide good results in weight loss and resolution of comorbidities at 18 months. 1. Introduction The obesity epidemic continues to increase worldwide and is associated with many comorbidities resulting in increased mortality rates of obese people [1, 2]. These comorbidities not only lead to a reduction in life expectancy, but also in quality of life [3]. And surgery remains the only proven treatment modality [4, 5]. Presently advocated Laparoscopic Roux-en-Y gastric bypass (LRYGB) is the most frequently performed bariatric procedure providing significant and sustained weight loss at long-term followup [6, 7]. The laparoscopic sleeve gastrectomy (LSG), initially used in patients with high surgical risk as the first stage of a more complex procedure (duodenal switch or gastric bypass), has gained popularity in recent years due to reported good short-term results and its relatively lower technical complexity [5–10]. However, the long-term efficacy is under investigation and there are very few studies that compare it with other bariatric techniques, including LRYGB. The purpose of this study was to retrospectively compare the early results of LRYGB and LSG for a period of 18 months and follow them up over a period of 5 years to see if LSG can replace LRYGB as the gold standard bariatric procedure in France. 2. Material and Methods The study was done at the university hospital in
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