The existence of six solutions for nonlinear operator equations is obtained by using the topological degree and fixed point index theory. These six solutions are all nonzero. Two of them are positive, the other two are negative, and the fifth and sixth ones are both sign-changing solutions. Furthermore, the theoretical results are applied to elliptic partial differential equations. 1. Introduction In recent years, motivated by some ecological problems, much attention has been attached to the existence of sign-changing solutions for nonlinear partial differential equations (see [1–4] and the references therein). We note that the proofs of main results in [1–4] depend upon critical point theory. However, some concrete nonlinear problems have no variational structures [5]. To overcome this difficulty, in [6], Zhang studied the existence of sign-changing solution for nonlinear operator equations by using the cone theory and combining uniformly positive condition. Xu [7] studied multiple sign-changing solutions to the following -point boundary value problems: where , , . We list some assumptions as follows.(A1)Suppose that the sequence of positive solutions to the equation ?is ;(A2) , is a continuous function, , and for all ;(A3)let and . There exist positive integers and such that (A4)there exists such that for all with . Theorem 1 (see [7]). Suppose that conditions are satisfied. Then the problem (1) has at least two sign-changing solutions. Moreover, the problem (1) also has at least two positive solutions and two negative solutions. Based on [7], many authors studied the sign-changing solutions of differential and difference equations. For example, Yang [8] considered the existence of multiple sign-changing solutions for the problem (1). Compared with Theorem 1, Yang employed the following assumption which is different from .(A′4)There exists such that Pang et al. [9] investigated multiple sign-changing solutions of fourth-order differential equation boundary value problems. Moreover, Wei and Pang [10] established the existence theorem of multiple sign-changing solutions for fourth-order boundary value problems. Y. Li and F. Li [11] studied two sign-changing solutions of a class of second-order integral boundary value problems by computing the eigenvalues and the algebraic multiplicities of the corresponding linear problems. He et al. [12] discussed the existence of sign-changing solutions for a class of discrete boundary value problems, and a concrete example was also given. Very recently, Yang [13] investigated the following discrete fourth Neumann
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