Lipomas are rare in oral and maxillofacial regions although they are the most common tumours of mesenchymal origin in human body. The etiology remains unclear. Various different theories explain the pathogenesis of this adipose tissue tumour and also different histological variants of oral lipoma have been given in literature. A case of intraoral lipoma occurring in mental region in a 77-year-old male is reported along with review of the literature. Wide surgical excision was performed and two-year followup showed excellent healing without any recurrence. Lipomas are benign soft tissue neoplasm of mature adipose tissue seen as a common entity in the head and neck region. Intraoral lipomas are a rare entity which may be noticed only during routine dental examinations. Most of them rarely cause pain, resulting in delay to seek treatment. It is mandatory for a clinician to diagnose intraoral lipomas using latest diagnostic methods and conservatively treat them without causing much discomfort. 1. Introduction Lipomas are the most common soft tissue neoplasm, representing 0.1 to 5% of all benign tumors of the mouth. About 15 to 20% of the cases involve the head and neck region, while 1–4% affect the oral cavity, an uncommon site for the occurrence of lipoma [1, 2]. Usually they are seen as long-standing soft nodular asymptomatic swellings covered by normal mucosa. They particularly occur in the areas of fat accumulation, especially the cheek, followed by the tongue, floor of the mouth, buccal sulcus and vestibule, lip, palate, and gingiva [3, 4]. Histologically, they can be classified as simple lipoma, fibrolipoma, spindle cell lipoma, intramuscular or infiltrating lipoma, angiolipoma, pleomorphic lipoma, myxoid lipoma, and atypical lipoma. Intramuscular or infiltrating lipoma is an uncommon mesenchymal tumor, usually appearing in the extremities or trunk but rarely occurring in the oral cavity [5]. Oral infiltrating lipomas are larger than the ordinary oral lipomas and present clinically as deep-seated, slow growing, painless masses [6]. Here we report a case of intraoral lipoma along with the review of literature. 2. Presentation of Case A 77-year-old male patient was referred to the Department of Oral and Maxillofacial Surgery with the complaint of swelling in relation to lower left mental region for the past year. The patient also complained of discomfort and feeling of heaviness in the area of the swelling. His medical history was noncontributory. Extra oral examination revealed a diffuse swelling in the left lower mental region, measuring 2 × 1?cm. On
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