A Case of Mucinous Cystadenofibroma of the Ovary

Ovarian adenofibroma is a rare benign tumour originating from the germinal lining and stroma of the ovary. We describe here the case of a 36-year-old woman with an ovarian mucinous cystadenofibroma that was diagnosed as a benign cystic mass of the ovary before surgery. The tumour was a cystic lesion composed of 2 regions: one filled with mucinous fluid and the other with yellowish solid components. The patient successfully underwent a left oophorectomy. 1. Introduction Ovarian cystadenofibroma is a very rare benign tumour that originates in the epithelium and includes diverse structures composed of cystic and solid fibrotic tissues. These tumours are classified, according to the epithelial cell types present, as serous, endometrioid, mucinous, clear cell, and mixed categories. Because ovarian cystadenofibroma presents as a multicystic mass with solid components, preoperative differential diagnosis is important to distinguish it from malignant neoplasms. In this report, we describe the treatment of a 36-year-old woman with an ovarian cyst. The lesion was not diagnosed as a benign tumour before surgery. After surgery, the tumour was diagnosed as a mucinous cystadenofibroma. 2. Case A 35-year-old gravid (1-0-0-1) woman presented with left lower abdominal pain for several years. Her menstrual cycle length was 30 days, menstruation volume was normal, and she experienced slight menstrual pain. Her family history was uneventful. Upon comprehensive medical testing, an ovarian mass was detected by pelvic CT. After the patient was transferred to our hospital, she underwent pelvic MRI. The MRI showed a 6 cm left ovary mass with numerous small cysts and a fibrous septal structure. At the time of admission, the patient’s blood pressure was 140/80？mmHg, her pulse was 74？bpm, her temperature was 36.5°C, and her general condition was good. During a pelvic examination, a painless cystic mass was detected in the left adnexal area. Blood test results were normal: haemoglobin level, 12.9？g/dL; red blood cell volume, 38.7%; leukocyte count, 6.380; and platelet count, 235,000. Results of urinalysis and blood chemistry analysis were within normal ranges. Serum concentrations of the tumour markers CA-125 and CA19-9 were 18.08 and 55.72？ng/mL, respectively; the CA19-9 tumour marker level was slightly elevated compared to normal. Transvaginal sonography performed at our hospital showed that the uterus was deviated to the right; no other notable features were observed, except for the left ovarian tumour, approximately 6 × 6？cm in size, with a septum. The inside of the tumour