To review pharmacist-led screening programmes for estimation of cardiovascular disease (CVD) risk using validated screening tools, studies were identified using a search of the following electronic databases: PubMed, EMBASE, Web of Knowledge and the Cochrane library databases. Each database was searched from inception to December 2011. The search terms used were: “cardiovascular disease”, “screening”, “risk estimation”, “pharmacist” and “pharmacy”. Titles, abstracts and full manuscripts were screened to determine eligibility. Inclusion criteria were: (i) Pharmacist-led CVD screening; and (ii) Use of validated screening tool or tools for CVD. From each included study information was collected on the following: Study author; year of publication; setting; inclusion and exclusion criteria; tools used and outcomes measured. Articles were grouped and independently verified to ensure they met with the inclusion criteria. Over 7,000 citations were found. Twenty full-length articles were retrieved for analysis, of which twelve were excluded, as they did not meet the inclusion criteria. The eight remaining articles were included in this literature review. Whilst pharmacists undertake screening in their own practice, this approach will only go so far. To have a population-health impact, pharmacists should be involved in proactive screening in a variety of settings.
References
[1]
World Health Organisation. The Global Burden of Disease: 2004 Update; World Health Organisation: Geneva, Switzerland, 2008.
[2]
World Health Organisation. The World Health Report 1999—Making A Difference; World Health Organisation: Geneva, Switzerland, 1999.
[3]
World Health Organisation. Cardiovascular Diseases (CVDs). Available online: http://www.who.int/mediacentre/factsheets/fs317/en/ (accessed on 7 December 2013).
[4]
Leong, T.; McGorrian, C.; Graham, I.M. Cardiovascular Epidemiology: Background and Principles of Cardiovascular Disease Prevention. In Therapeutic Strategies in Cardiovascular Risk; Graham, I.M., D’Agostino, R.B., Sr, Eds.; Clinical Publishing: Oxford, UK, 2008; pp. 5–16.
[5]
Myerburg, R.J.; Kessler, K.M.; Castellanos, A. Sudden cardiac death: Epidemiology, transient risk, and intervention assessment. Ann. Intern. Med. 1993, 119, 1187–1197, doi:10.7326/0003-4819-119-12-199312150-00006.
[6]
Oriol-Zerbe, C.; Abholz, H.H. Primary prevention of cardiovascular diseases by lipid-lowering treatment in German general practice: Results from GPs ignoring guidelines and risk calculators. Eur. J. Gen. Pract. 2007, 13, 27–34, doi:10.1080/13814780601050541.
[7]
Graham, I.M.; Stewart, M.; Hertog, M.G. Factors impeding the implementation of cardiovascular prevention guidelines: Findings from a survey conducted by the European Society of Cardiology. Eur. J. Cardiovasc. Prev. Rehabil. 2006, 13, 839–45, doi:10.1097/01.hjr.0000219112.02544.24.
[8]
Persson, M.; Carlberg, B.; Tavelin, B.; Lindholm, L.H. Doctors’ estimation of cardiovascular risk and willingness to give drug treatment in hypertension: Fair risk assessment but defensive treatment policy. J. Hypertens. 2004, 22, 65–71.
[9]
Kenny, N.; ní Ríain, A. Cardiovascular Disease in Women Quick Reference Guide. Available online: http://www.icgp.ie/go/library/catalogue/item/1A93A7E1-C87C-4029-87047A279C74B036/ (accessed on 7 December 2013).
[10]
National Cholesterol Education Program. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of High Blood Cholesterol in adults (Adult Treatment Panel III) final report. Circulation 2002, 106, 3143–3421.
[11]
Conroy, R.M.; Pyorala, K.; Fitzgerald, A.P.; Sans, S.; Menotti, A.; de Backer, G.; de Bacquer, D.; Ducimetière, P.; Jousilahti, P.; Keil, U.; et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: The SCORE project. Eur. Heart J. 2003, 24, 987–1003, doi:10.1016/S0195-668X(03)00114-3.
[12]
D’Agostino, R.B., Sr; Vasan, R.S.; Pencina, M.J.; Wolf, P.A.; Cobain, M.; Massaro, J.M.; Kannel, W.B. General cardiovascular risk profile for use in primary care: The Framingham Heart Study. Circulation 2008, 117, 743–753, doi:10.1161/CIRCULATIONAHA.107.699579.
[13]
Hippisley-Cox, J.; Coupland, C.; Vinogradova, Y.; Robson, J.; Minhas, R.; Sheikh, A.; Brindle, P. Predicting cardiovascular risk in England and Wales: Prospective derivation and validation of QRISK2. BMJ 2008, 336, 1475–1482, doi:10.1136/bmj.39609.449676.25.
[14]
Woodward, M.; Brindle, P. Tunstall-Pedoe H and estimation Sgor. Adding social deprivation and family history to cardiovascular risk assessment: The ASSIGN score from the Scottish Heart Health Extended Cohort (SHHEC). Heart 2007, 93, 172–176, doi:10.1136/hrt.2006.108167.
[15]
Dawber, T.R.; Kannel, W.B.; Revotskie, N.; Kagan, A. The epidemiology of coronary heart disease—the framingham enquiry. Proc. R. Soc. Med. 1962, 55, 265–271.
[16]
Graham, I.A.D.; Borch-Johnsen, K.; Boysen, G.; Burell, G.; Cifkova, R.; Dallongeville, J.; de Backer, G.; Ebrahim, S.; Gjelsvik, B.; Herrmann-Lingen, C.; et al. European guidelines on cardiovascular disease prevention in clinical practice: Executive summary: Fourth joint task force of the european society of cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur. Heart J. 2007, 28, 2375–2414, doi:10.1093/eurheartj/ehm316.
[17]
O’Loughlin, J.; Masson, P.; Dery, V.; Fagnan, D. The role of community pharmacists in health education and disease prevention: A survey of their interests and needs in relation to cardiovascular disease. Prev. Med. 1999, 28, 324–331, doi:10.1006/pmed.1998.0436.
[18]
Van Mil, J.W.; Schulz, M.; Tromp, T.F. Pharmaceutical care, European developments in concepts, implementation, teaching, and research: A review. Pharm. World Sci. 2004, 26, 303–311.
[19]
World Health Organisation. New tool to enhance role of pharmacists in health care. Available online: http://www.who.int/mediacentre/news/new/2006/nw05/en/ (accessed on 13 December 2013).
[20]
Dorevitch, A.; Perl, E. The impact of clinical pharmacy intervention in a psychiatric hospital. J. Clin. Pharm. Ther. 1996, 21, 45–48, doi:10.1111/j.1365-2710.1996.tb00347.x.
[21]
Cote, I.; Moisan, J.; Chabot, I.; Gregoire, J.P. Health-related quality of life in hypertension: Impact of a pharmacy intervention programme. J. Clin. Pharm. Ther. 2005, 30, 355–362, doi:10.1111/j.1365-2710.2005.00663.x.
[22]
Murray, M.D.; Ritchey, M.E.; Wu, J.; Tu, W. Effect of a pharmacist on adverse drug events and medication errors in outpatients with cardiovascular disease. Arch. Intern. Med. 2009, 169, 757–763, doi:10.1001/archinternmed.2009.59.
[23]
Tsuyuki, R.T.; Johnson, J.A.; Teo, K.K.; Ackman, M.L.; Biggs, R.S.; Cave, A.; Chang, W.C.; Dzavik, V.; Farris, K.B.; Galvin, D.; et al. Study of Cardiovascular Risk Intervention by Pharmacists (SCRIP): A randomized trial design of the effect of a community pharmacist intervention program on serum cholesterol risk. Ann. Pharmacother. 1999, 33, 910–919, doi:10.1345/aph.18380.
O’Donovan, D.ó.; Byrne, S.; Sahm, L. The role of pharmacists in control and management of type 2 Diabetes Melitus: A review of the literature. Available online: http://www.journalofdiabetology.org/Pages/Releases/FullTexts/FourthIssue/RA-1-JOD-10-023.aspx (accessed on 18 December 2013).
[26]
Rothman, R.L.; Malone, R.; Bryant, B.; Shintani, A.K.; Crigler, B.; Dewalt, D.A.; Dittus, R.S.; Weinberger, M.; Pignone, M.P. A randomized trial of a primary care-based disease management program to improve cardiovascular risk factors and glycated hemoglobin levels in patients with diabetes. Am. J. Med. 2005, 118, 276–284, doi:10.1016/j.amjmed.2004.09.017.
[27]
Carter, B.L.; Bergus, G.R.; Dawson, J.D.; Farris, K.B.; Doucette, W.R.; Chrischilles, E.A.; Hartz, A.J. A cluster randomized trial to evaluate physician/pharmacist collaboration to improve blood pressure control. J. Clin. Hypertens. (Greenwich) 2008, 10, 260–271, doi:10.1111/j.1751-7176.2008.07434.x.
[28]
McLean, D.L.; McAlister, F.A.; Johnson, J.A.; King, K.M.; Makowsky, M.J.; Jones, C.A.; Tsuyuki, R.T. A randomized trial of the effect of community pharmacist and nurse care on improving blood pressure management in patients with diabetes mellitus: Study of cardiovascular risk intervention by pharmacists-hypertension (SCRIP-HTN). Arch. Intern. Med. 2008, 168, 2355–2361, doi:10.1001/archinte.168.21.2355.
[29]
Gattis, W.A.; Hasselblad, V.; Whellan, D.J.; O’Connor, C.M. Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: Results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study. Arch. Intern. Med. 1999, 159, 1939–1945, doi:10.1001/archinte.159.16.1939.
[30]
Evans, C.D.; Eurich, D.T.; Taylor, J.G.; Blackburn, D.F. The Collaborative Cardiovascular Risk Reduction in Primary Care (CCARP) study. Pharmacotherapy 2010, 30, 766–775, doi:10.1592/phco.30.8.766.
[31]
Peterson, G.M.; Fitzmaurice, K.D.; Kruup, H.; Jackson, S.L.; Rasiah, R.L. Cardiovascular risk screening program in Australian community pharmacies. Pharm. World Sci. 2010, 32, 373–380, doi:10.1007/s11096-010-9379-8.
[32]
Donyai, P.; van den Berg, M. Coronary heart disease risk screening: The community pharmacy Healthy Heart Assessment Service. Pharm. World Sci. 2009, 31, 643–647, doi:10.1007/s11096-009-9338-4.
[33]
De Oliveira, M.S.; e Silva, S.P.; Papoila, A.L.; Caramona, M.; van Mil, F.J.; Cabrita, J. Assessment of global cardiovascular risk and risk factors in Portugal according to the SCORE？ model. J. Public Health 2008, 16, 361–367, doi:10.1007/s10389-008-0183-z.
[34]
Liu, Y.; Mentele, L.J.; McDonough, R.P.; Carruthers, K.M.; Doucette, W.R. Community pharmacist assessment of 10-year risk of coronary heart disease for union workers and their dependents. J. Am. Pharm. Assoc. 2008, 48, 515–517, doi:10.1331/JAPhA.2008.07099.
[35]
Olenak, J.L.; Calpin, M. Establishing a cardiovascular health and wellness program in a community pharmacy: screening for metabolic syndrome. J. Am. Pharm. Assoc. 2010, 50, 32–36, doi:10.1331/JAPhA.2010.08104.
[36]
Horgan, J.M.; Blenkinsopp, A.; McManus, R.J. Evaluation of a cardiovascular disease opportunistic risk assessment pilot (‘Heart MOT’ service) in community pharmacies. J. Public Health 2010, 32, 110–116, doi:10.1093/pubmed/fdp092.
[37]
Dawber, T.R.; Meadors, G.F.; Moore, F.E., Jr. Epidemiological approaches to heart disease: The Framingham Study. Am. J. Public Health Nations Health 1951, 41, 279–281, doi:10.2105/AJPH.41.3.279.
[38]
Hippisley-Cox, J.; Coupland, C.; Vinogradova, Y.; Robson, J.; May, M.; Brindle, P. Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: Prospective open cohort study. BMJ 2007, 335, 136, doi:10.1136/bmj.39261.471806.55.
[39]
Family Heart Study Group. British family heart study: Its design and method, and prevalence of cardiovascular risk factors. Br. J. Gen. Pract. 1994, 44, 62–67.
[40]
Family Heart Study Group. Randomised controlled trial evaluating cardiovascular screening and intervention in general practice: Principal results of British family heart study. BMJ 1994, 308, 313–320, doi:10.1136/bmj.308.6924.313.
[41]
BreastCheck Programme Report 2010–2011. Available online: http://www.breastcheck.ie/sites/default/files/breastcheck_pogramme_report_2010-2011.pdf (accessed on 12 November 2013).
