By reference to modern genetic disease diagnostic criteria, there were 89 cases with symptoms relevant to genetic inheritance reported in the chapter Wu Xing Zhi:5 Elements of the 24 books and historical manuscripts of Qing dynasty of China. Ten types of genetic disorders were described: interaction between genetic and environment, congenital of genetic heterogeneity, chromosome abnormality, polygene, dominant, recombination, mutation, tumor, expressing abnormal and no explaining cause.