尿素通道蛋白B的转运特性
Transport Characteristics of Urea Transporter-B

DOI: 10.12677/JPS.2014.21001, PP. 1-4

Keywords: 尿素通道蛋白B；尿素；尿素类似物；NH3；水
UT-B, Urea, Urea Analogues, Ammonia, Water

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Abstract:

尿素通道蛋白B(urea transporters B, UT-B)主要表达在红细胞和一些上皮及内皮细胞膜，介导尿素的跨膜转运。近年来研究发现UT-B亦参与其他物质的转运，如水、NH₃和尿素类似物等，提示UT-B还可以作为水和气体通道。本文主要阐述UT-B对这些物质的转运特性，并探究其可能的生理学意义。

Urea transporter UT-B is highly expressed in the membrane of erythrocytes and some epithelial and endothelial cells, in which UT-B facilitates urea transport. Recently, studies find that water, ammonia and urea analogues can also be transported by UT-B. This review mainly focuses on the transport characteristics of UT-B, and the possible physiological significance will be discussed as well.

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