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盐酸文拉法辛的合成
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Abstract:
以廉价易得的茴香醇为原料，经7步反应以56.7%的总收率合成得到盐酸文拉法辛。该路线简捷高效，反应条件温和，后处理操作简单，适合工业化生产。
Venlafaxine hydrochloride was synthesized via 7-step reactions in the total yield of 56.7% from anisic alcohol. The synthetic route is concise and efficient, and suitable for industrialization due to its mild reaction conditions and simple post-treatment.
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