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Alumina Supported Synthesis of Some α,β– Unsaturated Heterocyclic AcidsDOI: 10.3126/jncs.v29i0.9229, PP. 1-4 Keywords: Solid support,Microwave irradiations,Condensation,Decarboxylation,One pot synthesis,Heterocyclic acids Abstract: Solid supported synthesis of some novel 3- (5'- substituted-2-furyl/thienyl) propen -2- oic acids has been carried out from malonic acid and 5- substituted furan/thiophene-2-carboxaldehydes under microwave irradiations in solvent free condition. The reaction completed in one step via condensation affording 88-96% of yield within 4-6 minutes. The reactions are accompanied with easy work-up, limited use of organic solvents and the use of inexpensive and hazard- free chemicals.? DOI: http://dx.doi.org/10.3126/jncs.v29i0.9229 Journal of Nepal Chemical Society Vol. 29, 2012 Page: 1-4 Uploaded date : 12/3/2013 ?
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