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乙肝病毒cccDNA的研究现状
The Research Status of Hepatitis B Virus cccDNA

DOI: 10.12677/IS.2015.32002, PP. 13-18

Keywords: 乙型肝炎病毒,松弛环状双链DNA,共价闭合环状DNA
HBV
, rcDNA, cccDNA

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Abstract:

乙型肝炎病毒(HBV)是一种小DNA病毒,共价闭合环状DNA (cccDNA)是HBV的原始复制模板,对乙肝病毒的复制及感染状态的建立具有重要意义。本文旨在对近年来有关cccDNA的形成、常用检测方法、抗病毒药物对其的影响等方面的进展作一综述报道。
The hepatitis B virus (HBV) is a kind of small DNA virus. The original template of covalently closed circular DNA (cccDNA) HBV is very important for the replication of the hepatitis B virus and the establishment of infection status. The progress of the formation of cccDNA, the methods of detection and the impact of antiviral drugs were reviewed in this paper.

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