World Health Organization, Wellcome Trust. Secondary prevention of non-communicable disease in low and middle income countries through community-based and health service interventions. Geneva, 2002. . Accessed July 10, 2015. WHO Report.
[3]
Wald NJ, Law MR. A strategy to reduce cardiovascular disease by more than 80%. BMJ. 2003; 326:1419. pmid:12829553 doi: 10.1136/bmj.326.7404.1419
[4]
Capewell S, Graham H. Will cardiovascular disease prevention widen health inequalities? PLoS Medicine. 2010; 7(8):e1000320. doi: 10.1371/journal.pmed.1000320. pmid:20811492
[5]
de Cates AN, Farr MR, Wright N, Jarvis MC, Rees K, Ebrahim S, et al. Fixed-dose combination therapy for the prevention of cardiovascular disease. Cochrane Database Syst Rev. 2014; 4:CD009868. doi: 10.1002/14651858.CD009868.pub2. pmid:24737108
[6]
Thom S, Poulter N, Field J, Patel A, Prabhakaran D, Stanton A, et al. Effects of a Fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of cardiovascular disease: The UMPIRE randomized clinical trial. JAMA. 2013; 310(9):918. doi: 10.1001/jama.2013.277064. pmid:24002278
[7]
Castellano JM, Sanz G, Pe？alvo JL, Bansilal S, Fernandez Ortiz A, Alvarez L, et al. A polypill strategy to improve adherence. J Am Coll Cardiol. 2014; 64(20):2071–82. doi: 10.1016/j.jacc.2014.08.021. pmid:25193393
[8]
Patel A, Cass A, Peiris D, Usherwood T, Brown A, Jan S, et al. A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk. Eur J Prev Cardiol. 2014; 22:920–930. doi: 10.1177/2047487314530382. pmid:24676715
[9]
Selak V, Elley CR, Bullen C, Crengle S, Wadham A, Rafter N, et al. Effect of fixed dose combination treatment on adherence and risk factor control among patients at high risk of cardiovascular disease: randomised controlled trial in primary care. BMJ. 2014; 348:g3318–8. doi: 10.1136/bmj.g3318. pmid:24868083
[10]
Huffman MD, Perel P, Castellano JM, Fuster V, Rodgers A, Webster R, et al. An application to recommend that fixed-dose combination therapy be added to the WHO model list of essential medicines for secondary prevention of cardiovascular disease (ischemic heart disease and ischemic stroke). . Accessed 27 May 2015.
[11]
Webster R, Patel A, Billot L, Cass A, Burch C, Neal B, et al. Prospective meta-analysis of trials comparing fixed dose combination based care with usual care in individuals at high cardiovascular risk: The SPACE Collaboration. Int J Cardiol. 2013; 170(1):30–5. doi: 10.1016/j.ijcard.2013.10.007. pmid:24144927
[12]
Huffman MD, Yusuf S. Polypills: essential medicines for cardiovascular disease secondary prevention? J Am Coll Cardiol. 2014; 63(14):1368–70. doi: 10.1016/j.jacc.2013.08.1665. pmid:24561141
[13]
Fontana M, Asaria P, Moraldo M, Finegold J, Hassanally K, Manisty CH, et al. Patient-accessible tool for shared decision making in cardiovascular primary prevention: balancing longevity benefits against medication disutility. Circulation. 2014; 129: 2539–46. doi: 10.1161/CIRCULATIONAHA.113.007595. pmid:24744274
[14]
Working Group on the Summit on Combination Therapy for CVD. Combination pharmacotherapy to prevent cardiovascular disease: present status and challenges. Eur Heart J. 2014; 35(6):353–64. doi: 10.1093/eurheartj/eht407. pmid:24288261
[15]
Viera AJ, Sheridan SL, Edwards T, Soliman EZ, Harris R, Furberg CD. Acceptance of a polypill approach to prevent cardiovascular disease among a sample of U.S. physicians. Prev Med. 2011 Jan;52(1):10–5. doi: 10.1016/j.ypmed.2010.09.016. pmid:20933538
[16]
Stone NJ, Robinson J, Lichtenstein AH, Merz CNB, Blum CB, Eckel RH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014; 129(25 Suppl 2):S49–73. doi: 10.1161/01.cir.0000437741.48606.98. pmid:24222018
[17]
Tricoci P, Allen JM, Kramer JM, Califf RM, Smith SCJ. Scientific evidence underlying the ACC/AHA clinical practice guidelines. JAMA. 2009;301(8):831–41. doi: 10.1001/jama.2009.205. pmid:19244190
[18]
James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. Evidence-based guideline for the management of high blood pressure in adults. JAMA. 2013; 311: 507–20. doi: 10.1001/jama.2013.284427
[19]
Choudhry NK, Avorn J, Glynn RJ, Antman EM, Schneeweiss S, Toscano M, et al. Full coverage for preventive medications after myocardial infarction. N Engl J Med. 2011; 365(22):2088–97. doi: 10.1056/NEJMsa1107913. pmid:22080794
[20]
Nieuwlaat R, Wilczynski N, Navarro T, Hobson N, Jeffery R, Keepanasseril A, et al. Interventions for enhancing medication adherence. Cochrane Database Syst Rev. 2014; 11:CD000011. doi: 10.1002/14651858.CD000011.pub4. pmid:25412402
[21]
Fenn J, LeHong H. Hype cycle for emerging technologies, 2011. Gartner. 2011.
