This study analyzed the association between household-level ecologic and individual-level sociodemographic determinants and dengue transmission in urban areas of Chachoengsao province, Thailand. The ecologic and sociodemographic variables were examined by univariate analysis and multivariate logistic regression. In the ecologic model, dengue risk was related to households situated in the ecotope of residential mixed with commercial and densely populated urban residential areas (RCDENPURA) (aOR？=？2.23, ), high historical dengue risk area (aOR？=？2.06, ), and presence of household window screens (aOR？=？1.62, ). In the sociodemographic model, the dengue risk was related to householders aged >45 years (aOR？=？3.24, ), secondary and higher educational degrees (aOR？=？2.33, ), household members >4 persons (aOR？=？2.01, ), and community effort in environmental management by clean-up campaign (aOR？=？1.91, ). It is possible that the preventive measures were positively correlated with dengue risk because these activities were generally carried out in particular households or communities following dengue experiences or dengue outbreaks. Interestingly, the ecotope of RCDENPURA and high historical dengue risk area appeared to be very good predictors of dengue incidences. 1. Introduction Dengue virus, an Aedes mosquito-borne viral pathogen belonging to the family Flaviviridae, is the cause of dengue fever (DF) and dengue hemorrhagic fever (DHF). The emergence and reemergence of DF/DHF have become a significant public health burden in the tropics and subtropics [1–5]. Due to the lack of an effective tetravalent dengue vaccine that can secure lifelong immunization, Aedes mosquito control measures have primarily been employed to prevent disease outbreak and interrupt transmission during the outbreak [6]. Regarded as a reemerging infectious disease [1, 4, 5], intermittent epidemics of DF and DHF have occurred in vulnerable populations. Such outbreaks reflect the failure of current prevention and control efforts, despite the fact that some successful cases of vector control in the Americas, Cuba, and Singapore had shortened outbreak periods and stopped the diseases from spreading [7–9]. In some cases, an application of appropriate vector control measures along with community participation have proven more effective and sustainable than antimosquito approaches alone [10–12]. Several reports have shown a coherent argument that transmission dynamics of dengue viruses result from very complex epidemiology and ecology of the disease. Such dengue transmission dynamics are the
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