This Staphylococcus epidermidis has been
discovered as the most frequent germ detected during indwelling medical devices
infection. This fact is well attached with the ability of this bacterium to
form structured layered population known as biofilm. Inside S. epidermidis biofilm, bacterial cells
present more different behavior than in their planktonic counterpart. This
paper describes the thriving application of Petri net theory for modeling of
interaction between different regulations actors leading S. epidermidis to switch from Planctonik to Biofilm. Indeed this
biologic system is very sensible and has dangerous effect. We propose Agent
Petri Nets model to describe and analyze the process of formation of Biofilm
molecule. This model presents a formal framework based on Multi Agents system
characteristics.
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