Background: Relationship between abnormal posture and QOL of Parkinson's disease is not clear.
Objectives: To clarify the association between quality of life (QOL) and abnormal posture in patients
with Parkinson’s disease (PD) and examine which QOL dimensions are involved. Methods:
This study retrospectively examined PD patients (n = 57) who had undergone outpatient rehabilitation
between January and March 2014. Evaluation items were Modified Hoehn Yahr (H-Y) stage,
Unified Parkinson’s Disease Rating Scale (UPDRS)-Part III score, Timed Up and Go test (TUG, 3-m
walking) result, Parkinson’s Disease Questionnaire (PDQ)-39 score, and the angle of forward and
lateral trunk flexion in the standing position. Statistical analysis was performed to reveal the relationship
between the total PDQ-39 score and individual evaluation items and which QOL dimensions
were affected by abnormal posture due to forward or lateral flexion. Results: A total of 38 PD
patients (17 men, 21 women; mean age, 73.2 ± 8.6 years) were enrolled. Among the evaluation
items, lateral flexion angle showed a significant correlation with the total PDQ-39 score (r = 0.422,
P = 0.008). PDQ-39 dimensions showing an association with forward flexion were activities of daily
living (ADL) (P = 0.002) and communication (P = 0.007), whereas ADL (P = 0.004), communication
(P = 0.021), and social support (P = 0.029) were associated with lateral flexion. Mobility was
not associated with forward or lateral flexion. Conclusion: The present findings revealed a correlation
between lateral flexion and QOL in PD patients. Among the PDQ-39 dimensions, ADL and
communication were associated with abnormal posture.
References
[1]
Yamawaki, M., Kusumi, M., Kowa, H. and Nakashima, K. (2009) Changes in Prevalence and Incidence of Parkinson’s Disease in Japan during a Quarter of a Century. Neuroepidemiology, 32, 263-269. http://dx.doi.org/10.1159/000201565
[2]
Gibb, W.R.G. and Lees, A.J. (1988) The Relevance of the Lewy Body to the Pathogenesis of Idiopathic Parkinson’s Disease. Journal of Neurology, Neurosurgery, and Psychiatry, 51, 745-752. http://dx.doi.org/10.1136/jnnp.51.6.745
[3]
Schrag, A., Jahanshahi, M. and Quinn, N. (2000) What Contributes to Quality of Life in Patients with Parkinson’s Disease? Journal of Neurology, Neurosurgery, and Psychiatry, 69, 308-312. http://dx.doi.org/10.1136/jnnp.69.3.308
[4]
Global Parkinson’s Disease Survey Steering Committee (2002) Factors Impacting on Quality of Life in Parkinson’s Disease: Results from an International Survey. Movement Disorders, 17, 60-67. http://dx.doi.org/10.1002/mds.10010
[5]
Karlsen, K.H., Larsen, J.P., Tandberg, E. and Maeland, J.G. (1999) Influence of Clinical and Demographic Variables on Quality of Life in Patients with Parkinson’s Disease. Journal of Neurology, Neurosurgery, and Psychiatry, 66, 431- 435. http://dx.doi.org/10.1136/jnnp.66.4.431
[6]
Hagell, P. and Nygren, C. (2007) The 39-Item Parkinson’s Disease Questionnaire (PDQ-39) Revisited. Journal of Neurology, Neurosurgery, and Psychiatry, 78, 1191-1198. http://dx.doi.org/10.1136/jnnp.2006.111161
[7]
Parkinson, J. (2002) An Essay on the Shaking Palsy 1817. The Journal of Neuropsychiatry & Clinical Neurosciences, 14, 223-236. http://dx.doi.org/10.1176/jnp.14.2.223
[8]
Doherty, K.M., van de Warrenburg, B.P., Peralta, M.C., Silveira-Moriyama, L., Azulay, J.P., Gershanik, O.S. and Bloem, B.R. (2011) Postural Deformities in Parkinson’s Disease. The Lancet Neurology, 10, 538-549.
http://dx.doi.org/10.1016/S1474-4422(11)70067-9
[9]
Peto, V., Jenkinson, C., Fitzpartrick, R. and Greenhall, R. (1995) The Development and Validation of a Short Measure of Functioning and Well Being for Individuals with Parkinson’s Disease. Quality of Life Research, 4, 241-248.
http://dx.doi.org/10.1007/BF02260863
[10]
Jenkinson, C., Fitzpatrick, R., Peto, V., Greenhall, R. and Hyman, N. (1997) The Parkinson’s Disease Questionnaire (PDQ-39): Development and Validation of Parkinson’s Disease Summary Index Score. Age Ageing, 26, 353-357.
http://dx.doi.org/10.1093/ageing/26.5.353
[11]
Kohmoto, J., Ohbu, S., Nagaoka, M., Suzukamo, Y., Kihira, T., Mizuno, Y., Ito, Y., Yamaguti, T., Ohashi, Y., Fukuhara, S. and Kondo, T. (2003) Validation of the Japanese Version of the Parkinson’s Disease Questionnaire. Journal of Clinical Neurology, 43, 71-76.
[12]
Moore, O., Peretz, C. and Giladi, N. (2007) Freezing of Gait Affects Quality of Life of Peoples with Parkinson’s Disease beyond Its Relationship with Mobility and Gait. Movement Disorders, 22, 2192-2195.
http://dx.doi.org/10.1002/mds.21659
[13]
Ellis, T., de Goede, C.J., Feldman, R.G., Wolters, E.C., Kwakkel, G. and Wagenaar, R.C. (2005) Efficacy of a Physical Therapy Program in Patients with Parkinson’s Disease: A Randomised Controlled Trial. Archives of Physical Medicine and Rehabilitation, 86, 626-632. http://dx.doi.org/10.1016/j.apmr.2004.08.008
[14]
Schmitz-Hübsch, T., Pyfer, D., Kielwein, K., Fimmers, R., Klockgether, T. and Wüllner, U. (2005) Qigong Exercise for the Symptoms of Parkinson’s Disease: A Randomized, Controlled Pilot Study. Movement Disorders, 21, 543-548.
http://dx.doi.org/10.1002/mds.20705
[15]
Burini, D., Farabollini, B., Iacucci, S., Rimatori, C., Riccardi, G., Cappecci, M., Provinciali, L. and Ceravolo, M.G. (2006) A Randomised Controlled Cross-Over Trial of Aerobic Training versus Qigong in Advanced Parkinson’s Disease. Europa Medicophysica, 42, 231-238.
[16]
Ashburn, A., Fazakarley, L., Ballinger, C., Pickering, R., McLellan, L.D. and Fitton, C. (2007) A Randomised Controlled Trial of a Home-Based Exercise Programme to Reduce Risk of Falling among People with Parkinson’s Disease. Journal of Neurology, Neurosurgery, and Psychiatry, 78, 678-684. http://dx.doi.org/10.1136/jnnp.2006.099333
[17]
Goodwin, V.A., Richards, S.H., Taylor, R.S. and Campbell, J.L. (2008) The Effectiveness of Exercise Interventions for Patients with Parkinson’s Disease: A Systematic Review and Meta-Analysis. Movement Disorders, 23, 226-233.
http://dx.doi.org/10.1002/mds.21922
[18]
Grosset, D., Taurah, L., Burn, D.J., MacMahon, D., Forbes, A., Turner, K., Bowron, A., Walker, R., Findley, L., Foster, O., Patel, K., Clough, C., Castleton, B., Smith S., Carey, G., Murphy, T., Hill, J., Brechany, U., McGee, P., Reading, S., Brand, G., Kelly, L., Breen, K., Ford, S., Baker, M., Williams, A., Hearne, J., Qizilbash, N. and Chaudhuri, K.R. (2007) A Multicenter Longitudinal Observational Study of Changes in Self Reported Health Status in People with Parkinson’s Disease Left Untreated at Diagnosis. Journal of Neurology, Neurosurgery, and Psychiatry, 78, 465-469.
http://dx.doi.org/10.1136/jnnp.2006.098327
[19]
Ellerhorst-Ryan, J.M. (1996) Instruments to Measure Spiritual Status. In: Spilker, B., Ed., Quality of Life and Pharmacoeconomics in Clinical Trial, Lippincott Williams & Wilkins, New York, 145-153.
[20]
Cheng, E.M., Tonn, S., Swain-Eng, R., Factor, S.A., Weiner, W.J. and Bever Jr., C.T. (2010) Quality Improvement in Neurology: AAN Parkinson Disease Quality Measures: Report of the Quality Measurement and Reporting Subcommittee of the American Academy of Neurology. Neurology, 75, 2021-2027.
http://dx.doi.org/10.1212/WNL.0b013e3181ff96dd
[21]
Ven der Marck, M.A., Bloem, B.R., Borm, G.F., Overeem, S., Munneke, M. and Guttman, M. (2013) Effectiveness of Multidisciplinary Care for Parkinson’s Disease: A Randomized, Controlled Trial. Movement Disorders, 28, 605-611.
http://dx.doi.org/10.1002/mds.25194