全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Pulmonary Immunohistochemical Detection of Surfactant Protein A (SP-A) in Fatal Drowning

DOI: 10.4236/fmar.2016.43006, PP. 33-36

Keywords: Drowning, Autopsy, Immunohistochemistry, Surfactant Protein A, Pathology

Full-Text   Cite this paper   Add to My Lib

Abstract:

Drowning still remains one of the most difficult diagnoses in forensic pathology because macroscopic and microscopic autopsy findings are unspecific. An ideal diagnostic marker for drowning still needs to be developed, but some authors have recently studied SP-A as a marker of asphyxiation and drowning. The aim of this study is to compare the histopathological features and the SP-A immunohistochemical expression in lung tissue in the case of drowning with those determined by other causes to discriminate between cadaver submersion and drowning.

References

[1]  Saukko, P. and Knight, B. (2016) Knight’s Forensic Pathology. CRC Press, Boca Raton.
[2]  Piette, M.H.A. and De Letter, E.A. (2006) Drowning: Still a Difficult Autopsy Diagnosis. Forensic Science International, 163, 1-9. http://dx.doi.org/10.1016/j.forsciint.2004.10.027
[3]  Zhu, B.L., Ishida, K., Quan, L., Fujita, M.Q. and Maeda, K. (2000) Immunohistochemistry of Pulmonary Surfactant Apoprotein A in Forensic Autopsy: Reassessment in Relation to the Causes of Death. Forensic Science International, 113, 193-197. http://dx.doi.org/10.1016/S0379-0738(00)00264-4
[4]  Zhu, B.L., Ishida, K., Quan, L., Fujita, M.Q. and Maeda, H. (2001) Immunohistochemistry of Pulmonary Surfactant- Associated Protein A in Acute Respiratory Distress Syndrome. Legal Medicine, 3, 134-140.
http://dx.doi.org/10.1016/S1344-6223(01)00020-7
[5]  Zhu, B.L., Ishida, K., Quan, L., Li, D.R., Taniguchi, M., Fujita, M.Q., Maeda, H. and Tsuji, T. (2002) Pulmonary Immunohistochemistry and Serum Levels of a Surfactant-associated Protein A in Fatal Drowning. Legal Medicine, 4, 1-6. http://dx.doi.org/10.1016/S1344-6223(01)00051-7
[6]  Maeda, H., Fujita, M.Q., Zhu, B.L., Ishida, K., Quan, L., Oritani, S. and Taniguchi, M. (2003) Pulmonary Surfactant- Associated Protein A as a Marker of Respiratory Distress in Forensic Pathology: Assessment of the Immunohistochemical and Biochemical Findings. Legal Medicine, 5, S318-S321.
http://dx.doi.org/10.1016/S1344-6223(02)00160-8
[7]  Perez-Carceles, M.D., Sibon, A., Vizcaya, M.A., Osuna, E., Gomez-Zapata, M., Luna, A. and Martinez-Diaz, F. (2008) Histological Findings and Immunohistochemical Surfactant Protein A (SP-A) Expression in Asphyxia: Its Application in the Diagnosis of Drowning. Histology and Histopathology, 23, 1061-1068.
[8]  Stemberga, V., Stifter, S., Cuculic, D., Coklo, M. and Bosnar, A. (2009) Immunohistochemical Surfactant Protein-A Expression: Fatal Drowning vs. Postmortem Immersion. Medical Hypotheses, 72, 413-415.
http://dx.doi.org/10.1016/j.mehy.2008.11.024
[9]  Zhu, B.L., Ishida, K., Fujita, M.Q. and Maeda, K. (2000) Immunohistochemical Investigation of a Pulmonary Surfactant in Fatal Mechanical Asphyxia. International Journal of Legal Medicine, 113, 268-271.
http://dx.doi.org/10.1007/s004149900109
[10]  Heinrich, S., Hartl, D. and Griese, M. (2006) Surfactant Protein A—From Genes to Human Lung Disease. Current Medicinal Chemistry, 13, 3239-3252. http://dx.doi.org/10.2174/092986706778773112
[11]  Vacchiano, G., D’Armiento, F. and Torino, R. (2001) Is the Appearance of Macrophages in Pulmonary Tissue Related to Time of Asphyxia? Forensic Science International, 115, 9-14.
http://dx.doi.org/10.1016/S0379-0738(00)00301-7
[12]  Betz, P., Nerlich, A., Penning, R. and Eisenmenger, W. (1993) Alveolar Macrophages and the Diagnosis of Drowning. Forensic Science International, 62, 217-224.
http://dx.doi.org/10.1016/0379-0738(93)90210-2
[13]  D’Annibale, C. and Tacconi, M.P. (2000) Il Comportamento dei Macrofagi Alveolari Polmonari nelle Morti da Asfissia. Jura Medica, 13, 337-354.
[14]  Giammona, S.T. and Modell, J.H. (1967) Drowning by Total Immersion. Effects on Pulmonary Surfactant of Distilled Water, Isotonic Saline, and Sea Water. American Journal of Diseases of Children, 114, 612-616.
http://dx.doi.org/10.1001/archpedi.1967.02090270068005
[15]  Wright, J.R. (2003) Pulmonary Surfactant: A Front Line of Lung Host Defense. Journal of Clinical Investigation, 111, 1453-1455. http://dx.doi.org/10.1172/JCI200318650
[16]  Haagsman, H.P. and Diemel, R.V. (2001) Surfactant-Associated Proteins: Functions and Structural Variation. Comparative Biochemistry and Physiology. Part A, Molecular and Integrative Physiology, 129, 91-108. http://dx.doi.org/10.1016/S1095-6433(01)00308-7
[17]  Morita, M., Tabata, N. and Maya, A. (1985) Studies on Asphyxia: On the Changes of the Alveolar Walls of Rats in the Hypoxic State. Forensic Science International, 27, 81-92.
http://dx.doi.org/10.1016/0379-0738(85)90170-7
[18]  Kuroki, Y., Dempo, K. and Akino, T. (1986) Immunohistochemical Study of Human Pulmonary Surfactant Apoproteins with Monoclonal Antibodies. American Journal of Pathology, 124, 25-33.

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413