Introduction: Early puberty is defined by development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. In the West, one in five children out of 100,000 is concerned. Little information on sub-Saharan African patients exists concerning this pathology. Objective: To determine the etiology and clinical characteristics of early puberty in a cohort of Ivorian children. Methods: We conducted a cross-sectional study between 2015 and 2017 in children admitted to early puberty in the unique Endocrinology Service of the country. The epidemiology and clinical characteristics were assessed. Results: The eight patients involved were all females. Their mean age at diagnosis was 7 years and 3 months and the mean age of first symptoms begun at 5 years and 6 months. Seven patients had a central precocious puberty (CPP) including five cases of idiopathic CPP (ICPP) treated by (GnRH agonist) and two cases with secondary precocious puberty (SPP). One of them has a hypothalamic hamartoma and the other a sequelae of encephalopathy. The last case had a peripheral precocious puberty (PPP) causes by ovarian dystrophy. Conclusion: Our results confirm the predominance of idiopathic central precocious puberty particularly in girls.
References
[1]
Bouvatier, C. (2014) Early Puberty. Springer-Verlag.
[2]
Baron, S., Battin, J., David, A. and Limal, J.M. (2000) Precocious Puberty in Children Adopted from Foreign Countries. Pediatric Archives, 7, 809-816.
[3]
Fuqua, J.S. (2013) Treatment and Outcomes of Precocious Puberty: An Update. The Journal of Clinical Endocrinology & Metabolism, 98, 2198-2207.
https://doi.org/10.1210/jc.2013-1024
[4]
Glynn, J., Kayuni, N., Gondwe, L., Price, A. and Crampin, A. (2014) Earlier Menarche Is Associated with a Hygher Prevalence of Herpes Simplex Type-2 (HSV-2) in Young Women in Rural Malawi. eLife, 3, e01604.
https://doi.org/10.7554/eLife.01604
[5]
Marshall, W.A. and Tanner, J.M. (1969) Variations in pa TTERN of Pubertal Girls in Exchange. Archives of Disease in Childhood, 44, 291-303.
https://doi.org/10.1136/adc.44.235.291
[6]
Greulich, M.M. and Pyle, S.I. (1959) Radiographic Atlas of Skeletal Development of the Hand and Wrist. 2nd Edition, University Press, Stanford.
[7]
Tfifha, I.M., Dhahri, D., Ajmi, H., Mabrouk, S., Kadri, K., Chemli, J., Zouari, N., Hassayoun, S., Tlili, K. and Abroug, S. (2014) Different Appearance of Precocious Puberty: Clinical Outcome and Experiance (8 Squares). Archives of Disease in Childhood, 99, A278.
[8]
Nienaber, C.S. and Van Der Walt, D. (1991) True Idiopathic Precocious Puberty Presenting at Six Months of Age; a Case Report. European Journal of Obstetrics & Gynecology and Reproductive Biology, 38, 243-245.
https://doi.org/10.1016/0028-2243(91)90300-A
[9]
Beauloye, V. (2016) Early Puberty. Louvain Medical, 4, 279-282.
[10]
Chen, C., Zhang, Y., Sun, W., et al. (2017) Investigating the Relationship between Precocious Puberty and Obesity: A Cross-Sectional Study in Shanghai, China. BMJ Open, 7, e014004. https://doi.org/10.1136/bmjopen-2016-014004
[11]
Ayadi, K.K., Ehdi, M., Khannous, M.M., et al. (1996) Hypothalamic Hamartomas: about Seven Observations. Tunisia Medical, 74, 135-137.
[12]
Mbassi Awa, H.D., Abena Obama, M.T., Pondy, A., Pienkowski, C., Nko’o Amvene, S. and Mbede, J. (2011) Central Precocious Puberty Due to Hypothalamic Hamartoma in Cameroon. Med Trop (Mars), 71, 309-311.
[13]
Purper-Ouakil, D. and Didillon, A. (2016) Psychopathology Associated with Female Precocious Puberty. Encephale, 42, 453-457.
[14]
Okoumou-Moko, A., El Mghari, G. and Ansari, N. (2014) Precocious puberty and ancestral practices in Republic of Congo. Annals of Endocrinology, 75, 409.
https://doi.org/10.1016/j.ando.2014.07.466
[15]
Hachicha, M., Kammoun, Th., Loulou, F., Guirat, N., Mahfoudh, A., Jardak, N. and Triki, A. (2002) Les puberties précoces centrales: Etude de 9 observations. [Central Early Puberty: Study of 9 Cases]. Revue Maghrébine de Pédiatrie, 12, 75-85.
