全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Malignant Mixed Mullerian Tumours (Carcinosarcoma of Uterine Cervix) (MMMT): Case Report and Review of Literature

DOI: 10.4236/ojcd.2018.81001, PP. 1-5

Keywords: Carcinosarcoma, Cervix Uterine, Rare, Malignancy, Prognosis

Full-Text   Cite this paper   Add to My Lib

Abstract:

Carcinosarcoma of the uterine cervix are very rare malignancy of the female reproductive tract with poor prognosis. Only fifty cases have been reported in literature until 2013. We report a 49 years old Para 7 + 3 presenting with vaginal bleeding, offensive discharge with intermittent abdominal pain. On examination an impression of a cervical polyp was made. She had total abdominal hysterectomy and bilateral salpingoophorectomy. The histological diagnosis of carcinosarcoma of the uterine cervix was made. She had chemoradiation therapy as adjuvant therapy in view of the diagnosis. Although cancer of the cervix is the second commonest cancer worldwide and the leading cause of cancer death in women, this particular histological variant is very rare, as such no standard protocol of management developed for it yet and it carries a very poor prognosis.

References

[1]  Grayson, W., Taylor, L.F., Cooper, K. (2001) Carcinosarcoma of the Uterine Cervix: A Report of Eight Cases with Immunohistochemical Analysis and Evaluation of Human Papillomavirus Status. American Journal of Surgical Pathology, 25, 338-347.
https://doi.org/10.1097/00000478-200103000-00008
[2]  Munakata, S., Iwai, E., Tanaka, T., Nakamura, M. and Kanda, T. (2013) Malignant Müllerian Mixed Tumor of the Uterine Cervix with a Small Cell Neuroendocrine Carcinoma Component. Case Reports in Pathology, 2013, 5.
https://doi.org/10.1155/2013/630859
[3]  Clement, P.B., Zubovits, J.T., Young, R.H. and Scully, R.E. (1998) Malignant Mullerian Mixed Tumors of the Uterine Cervix: A Report of Nine Cases of a Neoplasm with Morphology often Different from Its Counterpart in the Corpus. International Journal of Gynecological Pathology, 17, 211-222.
https://doi.org/10.1097/00004347-199807000-00004
[4]  Ribeiro-Silva, A., Novello-Vilar, A., Cunha-Mercante, A.M. and De Angelo Andrade, L.A.L. (2002) Malignant Mixed Mullerian Tumor of the Uterine Cervix with Neuroendocrine Differentiation. International Journal of Gynecological Cancer, 12, 223-227.
https://doi.org/10.1046/j.1525-1438.2002.01100.x
[5]  Oguntayo, O.A., Zayyan, M., Kolawole, A.O.D., Adewuyi, S.A., IsmaIL, H. and Koledade, K. (2011) Cancer of the Cervix in Zaria, Northern Nigeria. Ecancermedical Science, 5, 219.
[6]  Oguntayo, O.A., Zayyan, M., Kolawole, A.O.D., Adewuyi, S.A. and Samaila, M.O.A. (2012) Epidemiology of Gynaecologic Cancers in Zaria, Northern Nigeria. Italian Journal of Gynaecology & Obstetricsvol, 24, 168-173.
[7]  World Health Organization (2002) Cervical Cancer Screening in Developing Countries: Report of a WHO Consultation. World Health Organization, Gneva, ISBN 92 4 154572 0.
[8]  Adekunle, O.O. and Samaila, M.O.A. (2010) Prevalence of Cervical Intraepithelial Neoplasia in Zaria. Annals of African Medicine, 9, 194-195.
https://doi.org/10.4103/1596-3519.68351
[9]  Kanthan, R. and Senger, J.L. (2011) Uterine Carcinosarcoma (Malignant Mixed Mullerian Tumour): A Review with Special Emphasis on Thr Controversies in Management. Obstetrics and Gynaecology International Volume, 2011, Article ID 470795.
https://doi.org/10.1155/2011/470795
[10]  Bosquet, J.S., Terstriep, S.A., Cliby, W.A., et al. (2010) The Impact of Multi-Modal Therapy on Survival for Uterine Carcinosarcoma. Gynecologic Oncology, 116, 419-423.
https://doi.org/10.1016/j.ygyno.2009.10.053
[11]  de Jong, R.A., Nijman, H.W., Wijbrandi, T.F., Reyners, A.K.L., Boezen, H.M. and Hollema, H. (2011) Molecular Makers and Clinical Behavior of Uterine Carcinosarcomas: Focus on Epithelia Tumour Component. Modern Pathology, 24, 1368-1379.
https://doi.org/10.1038/modpathol.2011.88

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413