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小檗碱药理作用研究进展
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Abstract:
[1] | 胡文祥, 等. 一种降糖及降脂药物组合物及其制备方法[P]. 中国发明专利, ZL200710179390.3. |
[2] | 韩谢, 邵开元, 胡文祥. 小檗碱结构修饰的研究进展[J]. 武汉工程大学学报, 2018, 40(1): 1-7. |
[3] | 韩谢, 邵开元, 胡文祥. 微波辐射合成9-氧-2-溴乙基小檗碱工艺研究[J]. 微波化学, 2017, 1(1): 8-14. |
[4] | Xie, H., Shao, K.Y. and Hu, W.X. (2018) Synthesis of 9-Substituted Berberine Derivatives with Microwave Irradiation. Chemical Research in Chinese Universities, 1, 1-7. |
[5] | Cao, J.X., Fu, L. and Sun, D.N. (2012) The Effect of Berberine on Arrhythmia Caused by Stretch of Myocardium, in Vitro, of Rats after Myocardial Ischemia. Chinese Journal of Emergency Medicine, 21, 683-686. |
[6] | Yu, F., Lin, M.S. and Zhang, W.D. (2009) Inhibition of Berberine on IKr, IKs and IK1 in Thyroxine Induced Cardiomyopathic Guinea Pig Ventricular Myocytes. Journal of China Pharmaceutical University, 40, 244-249. |
[7] | Fu, Y. (2011) Berberine Elicits Anti-Arrhythmic Effects via IK1/Kir2.1 in the Rat Type 2 Diabetic Myocardial Infarction Model. Phytotherapy Research, 25, 33-37. https://doi.org/10.1002/ptr.3097 |
[8] | Chen, H., Chen, Y., Tang, Y., et al. (2014) Berberine Attenuates Spontaneous Action Potentials in Sinoatrial Node Cells and the Currents of Human HCN4 Channels Expressed in Xenopus Laevis Oocytes. Molecular Medicine Reports, 10, 1576. https://doi.org/10.3892/mmr.2014.2377 |
[9] | Chang, W., Zhang, M., Li, J., et al. (2012) Berberine Attenuates Is-chemia-Reperfusion Injury via Regulation of Adenosine-5’-Monophosphate Kinase Activity in Both Non-Ischemic and Ischemic Areas of the Rat Heart. Cardiovascular Drugs & Therapy, 26, 467-478. https://doi.org/10.1007/s10557-012-6422-0 |
[10] | Zhang, T., Yang, S. and Du, J. (2014) Protective Effects of Ber-berine on Isoproterenol-Induced Acute Myocardial Ischemia in Rats through Regulating HMGB1-TLR4 Axis. Evi-dence-Based Complementray and Alternative Medicine, 11, 849783. |
[11] | Yu, L., Li, F., Zhao, G., et al. (2015) Protec-tive Effect of Berberine against Myocardial Ischemia Reperfusion Injury: Role of Notch1/Hes1-PTEN/Akt Signaling. Apoptosis, 20, 796. https://doi.org/10.1007/s10495-015-1122-4 |
[12] | Zhang, Y.J., Yang, S.H., Li, M.H., et al. (2014) Berberine Attenuates Adverse Left Ventricular Remodeling and Cardiac Dysfunction after Acute Myocardial Infarction in Rats: Role of Autophagy. Clinical & Experimental Pharmacology & Physiology, 41, 995. https://doi.org/10.1111/1440-1681.12309 |
[13] | Li, M.H., Zhang, Y.J., Yu, Y.H., et al. (2014) Berberine Improves Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction through Enhanced Autophagy. European Journal of Pharmacology, 728, 67-76.
https://doi.org/10.1016/j.ejphar.2014.01.061 |
[14] | Wang, J.L. and Fang, D.C. (1995) Influence of Berberine on Rat Cardiac Output and on the Effect of Ouabain in Guinea Pig Left Etria. Chinese Journal of Pharmacology and Toxicology, 5, 1 |
[15] | 黄伟民, 严桦, 于以庆, 等. 黄连素对冠状动脉的作用及机理[J]. 中华心血管病杂志, 1990, 18(4): 231. |
[16] | Shin, D.H., Yu, H. and Hsu, W.H. (1993) A Paradoxical Stimulatory Effect of Berberine on Guinea-Pig Ileum Contractility: Possible Involvement of Acetylcholine Release from the Postganglionic Parasympathetic Nerve and Cholinesterase Inhibition. Life Sciences, 53, 1495-1500. https://doi.org/10.1016/0024-3205(93)90623-B |
[17] | Wong, K.K. (1998) Mechanism of the Aortic Relaxation Induced by Low Concentrations of Berberine. Planta Medica, 64, 756-757. https://doi.org/10.1055/s-2006-957575 |
[18] | He, K., Kou, S., Zou, Z., et al. (2016) Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters. Planta Medica, 82, 690-697. https://doi.org/10.1055/s-0035-1568261 |
[19] | Thomson, D.M. and Winder, W.W. (2009) AMP-Activated Protein Kinase Control of Fat Metabolism in Skeletal Muscle. Acta Physiologica, 196, 147-154. https://doi.org/10.1111/j.1748-1716.2009.01973.x |
[20] | Jiang, J.D., Kong, W.J., Zhao, L.X., et al. (2007) Methods and Compositions for the Treatment of Hyperlipidemia. US EP 1796666 A1. |
[21] | Wang, C., Huang, Z., Wang, L., et al. (2014) Application of Berberine Derivative in Preparation of Drug for Treating Atherosclerosis. CN 103804374 A. |
[22] | Liu, H., Li, G., Wang, J., et al. (2011) Berberine Derivatives Useful for Modulating Lipid Levels and Their Methods of Synthesis: WO, WO/2011/006000. |
[23] | Salehi, S. (2009) Effects of Medicinal Herbs on Contraction Rate of Cultured Cardiomyocyte. Possible Mechanisms Involved in the Chronotropic Effects of Hawthorn and Berberine in Neonatal Murine Cardiomyocyte. Dissertations & Theses Gradworks. |
[24] | Zhang, X.D., Ren, H.M. and Liu, L. (2008) Effects of Different Dose Berberine on Hemodynamic Parameters and [Ca2+]i of Cardiac Myocytes of Diastolic Heart Failure Rat Model. China Journal of Chinese Materia Medica, 33, 818. |
[25] | Li, Y.M., Chen, X.C., Liu, H., et al. (2009) Effects of Ginseng Total Saponins with Berberine on Plasma Brain Natriuretic Pep Tide and Ca2+ Concentration in Experimental Rats with Chronic Congestive Heart Failure. China Journal of Chinese Materia Medica, 34, 324-327. |
[26] | Dong, S.F., Hong, Y., Liu, M., et al. (2011) Berberine Attenuates Cardiac Dysfunction in Hyperglycemic and Hypercholesterolemic Rats. European Journal of Pharmacology, 660, 368-374. https://doi.org/10.1016/j.ejphar.2011.03.024 |
[27] | Mizokami, S.S., Hohmann, M.S.N., Staurengoferrari, L., et al. (2016) Pimaradienoic Acid Inhibits Carrageenan-Induced Inflammatory Leukocyte Recruitment and Eedema in Mice: Inhibition of Oxidative Stress, Nitric Oxide and Cytokine Production. PLoS ONE, 11, e0149656. https://doi.org/10.1371/journal.pone.0149656 |
[28] | Cho, Y.J. (2011) Anti-Inflammatory Effect of Jatrorhizine form Phellodendron amurense in Lipopolysaccharide-Stimulated Raw 264.7 Cells. Journal of Applied Biological Chemistry, 54, 114-119.
https://doi.org/10.3839/jabc.2011.020 |
[29] | Yan, B., Wang, D., Dong, S., et al. (2017) Palmatine Inhibits TRIF-Dependent NF-κB Pathway against Inflammation Induced by LPS in Goat Endometrial Epithelial Cells. Interna-tional Immunopharmacology, 45, 194-200.
https://doi.org/10.1016/j.intimp.2017.02.004 |
[30] | Gambhir, S., Vyas, D., Hollis, M., et al. (2015) Nuclear Factor Kappa B Role in Inflammation Associated Gastrointestinal Malignancies. World Journal of Gastroenterology, 21, 3174. https://doi.org/10.3748/wjg.v21.i11.3174 |
[31] | Mishra, K.P., Sharma, N., Soree, P., et al. (2016) Hypoxia-Induced Inflammatory Chemokines in Subjects with a History of High-Altitude Pulmonary Edema. Indian Journal of Clinical Biochemistry, 31, 81-86.
https://doi.org/10.1007/s12291-015-0491-3 |
[32] | Cui, H.S., Hayasaka, S., Zhang, X.Y., et al. (2006) Effect of Berberrubine on Interleukin-8 and Monocyte Chemotactic Protein-1 Expression in Human Retinal Pigment Epithelial Cell Line. Life Sciences, 79, 949-956.
https://doi.org/10.1016/j.lfs.2006.05.004 |
[33] | Zhou, H. and Mineshita, S. (2000) The Effect of Berberine Chloride on Experimental Colitis in Rats in Vivo and in Vitro. Journal of Pharmacology & Experimental Therapeutics, 294, 822-829. |
[34] | Yang, T.C., Chao, H.F., Shi, L.S., et al. (2014) Alkaloids from Coptis Chinensis Root Promote Glucose Uptake in C2C12 Myotubes. Fitoterapia, 93, 239-244. https://doi.org/10.1016/j.fitote.2014.01.008 |
[35] | Hamid, A., Yusoff, M.M., Liu, M., et al. (2015) α-Glucosidase and α-Amylase Inhibitory Constituents of Tinospora Crispa: Isolation and Chemical Profile Confirmation by Ultra-High Performance Liquid Chromatography-Quadrupole Time-of-Flight/Mass Spectrometry. Journal of Functional Foods, 16, 74-80. https://doi.org/10.1016/j.jff.2015.04.011 |
[36] | 欧阳礼枝, 陆付耳. 小檗碱对胰岛素抵抗大鼠糖脂代谢影响的研究[J]. 中国药物与临床, 2010, 10(10): 1089-1091. |
[37] | Zhang, J., Tang, H., Deng, R., et al. (2015) Berberine Sup-presses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity. PLoS ONE, 10, e0125667. https://doi.org/10.1371/journal.pone.0125667 |
[38] | Choi, Y.J., Lee, K.Y., Jung, S.H., et al. (2017) Activation of AMPK by Berberine Induces Hepatic Lipid Accumulation by Upregulation of Fatty Acid Translocase CD36 in Mice. Toxicology & Applied Pharmacology, 316, 74-82.
https://doi.org/10.1016/j.taap.2016.12.019 |
[39] | Sun, Y., Xia, M., Yan, H., et al. (2018) Berberine Attenuates He-patic Steatosis and Enhances Energy Expenditure in Mice by Inducing Autophagy and Fibroblast Growth Factor 21. British Journal of Pharmacology, 175, 374-387.
https://doi.org/10.1111/bph.14079 |
[40] | Liang, K.W., Yin, S.C., Ting, C.T., et al. (2008) Berberine Inhibits Plate-let-Derived Growth Factor-Induced Growth and Migration Partly through an AMPK-Dependent Pathway in Vascular Smooth Muscle Cells. European Journal of Pharmacology, 590, 343-354. https://doi.org/10.1016/j.ejphar.2008.06.034 |
[41] | Hartmut, L., Mcmurray, H.R. and Sampson, E.R. (2009) Methods and Compositions Related to Synergistic Responses to Oncogenic Mutations. US, WO/2009/045443. |
[42] | Chung, J.G., Wu, L.T., Chu, C.B., et al. (1999) Effects of Berberine on Arylamine N-Acetyltransferase Activity in Human Bladder Tumour Cells. Food & Chemical Toxicology, 37, 319-326.
https://doi.org/10.1016/S0278-6915(99)00016-2 |
[43] | Lin, J.G., Chung, J.G., Wu, L.T., et al. (1999) Effects of Berberine on Arylamine N-Acetyltransferase Activity in Human Colon Tumor Cells. The American Journal of Chinese Medicine, 27, 265-275.
https://doi.org/10.1142/S0192415X99000306 |
[44] | Wang, D.Y., Yeh, C.C., Lee, J.H., et al. (2002) Berberine In-hibited Arylamine N-Acetyltransferase Activity and Gene Expression and DNA Adduct Formation in Human Malignant Astrocytoma (G9T/VGH) and Brain Glioblastoma Multiforms (GBM 8401) Cells. Neurochemical Research, 27, 883-889. https://doi.org/10.1023/A:1020335430016 |
[45] | Lin, S.S., Chung, J.G., Lin, J.P., et al. (2005) Berberine Inhibits Arylamine N-Acetyltransferase Activity and Gene Expression in Mouse Leukemia L1210 Cells. Phytomedicine, 12, 351. https://doi.org/10.1016/j.phymed.2003.11.008 |
[46] | Qin, Y., Pang, J.Y., Chen, W.H., et al. (2010) Inhibition of DNA Topoisomerase I by Natural and Synthetic Mono- and Dimeric Protoberberine Alkaloids. Chemistry & Biodiversity, 4, 481-487. https://doi.org/10.1002/cbdv.200790040 |
[47] | Hsieh, H.M., Lee, C.Y., Shen, C.C., et al. (2015) Berberine-Containing Pharmaceutical Composition for Inhibiting Cancer Stem Cell Growth or Carcinoma Metastasis and Application Thereof. US, US20150320738. |
[48] | Tin-Wa, M. (2007) Berberine as a Selective Lung Cancer Agent. US, US 20070298132 A1. |
[49] | Valko, M., Leibfritz, D., Moncol, J., et al. (2007) Free Radicals and Antioxidants in Normal Physiological Functions and Human Disease. International Journal of Biochemistry & Cell Biology, 39, 44-84.
https://doi.org/10.1016/j.biocel.2006.07.001 |
[50] | Jang, M.H., Kim, H.Y., Kang, K.S., et al. (2009) Hydroxyl Radical Scavenging Activities of Isoquinoline Alkaloids Isolated from Coptis chinensis. Archives of Pharmacal Research, 32, 341-345.
https://doi.org/10.1007/s12272-009-1305-z |
[51] | Boberek, J.M., Stach, J. and Good, L. (2010) Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine. PLoS ONE, 5, e13745. https://doi.org/10.1371/journal.pone.0013745 |
[52] | Peng, L., Shuai, K., Yin, Z., et al. (2015) Antibacterial Activity and Mechanism of Berberine against Streptococcus agalactiae. International Journal of Clinical and Experimental Pathology, 8, 5217-5223. |
[53] | Kang, S., Li, Z., Yin, Z., et al. (2015) The Antibacterial Mechanism of Berberine against Actinobacillus pleuropneumoniae. Natural Product Research, 29, 2203-2206. https://doi.org/10.1080/14786419.2014.1001388 |
[54] | Wojtyczka, R.D., Dziedzic, A., K?pa, M., et al. (2014) Berberine Enhances the Antibacterial Activity of Selected Antibiotics against Coagulase-Negative Staphylococcus Strains in Vitro. Molecules, 19, 6583-6596.
https://doi.org/10.3390/molecules19056583 |
[55] | Kong, W., Li, Z., Xiao, X., et al. (2010) Activity of Berberine on Shigella Dysenteriae, Investigated by Microcalorimetry and Multivariate Analysis. Journal of Thermal Analysis & Calorimetry, 102, 331-336.
https://doi.org/10.1007/s10973-010-0778-9 |
[56] | Wang, X., Qiu, S., Yao, X., et al. (2009) Berberine Inhibits Staphylococcus Epidermidis Adhesion and Biofilm Formation on the Surface of Titanium Alloy. Journal of Orthopaedic Research, 27, 1487. https://doi.org/10.1002/jor.20917 |
[57] | Wang, X., Yao, X., Zhu, Z., et al. (2009) Effect of Berberine on Staphylococcus Epidermidis Biofilm Formation. International Journal of Antimicrobial Agents, 34, 60-66. https://doi.org/10.1016/j.ijantimicag.2008.10.033 |
[58] | Bae, J., Lee, D., Yun, K.K., et al. (2013) Berberine Protects 6-Hydroxydopamine-Induced Human Dopaminergic Neuronal Cell Death through the Induction of Heme Oxygenase-1. Molecules & Cells, 35, 151-157.
https://doi.org/10.1007/s10059-013-2298-5 |
[59] | Chin, L.S.W., Cheng, Y.W., Lin, S.S., et al. (2010) Anti-Herpes Simplex Virus Effects of Berberine from Coptidis Rhizoma, a Major Component of a Chinese Herbal Medicine, Ching-Wei-San. Archives of Virology, 155, 1933-1941.
https://doi.org/10.1007/s00705-010-0779-9 |
[60] | Dkhil, M.A. and Al-Quraishy, S. (2014) Evaluation of Antiviral Activity of Berberine against Herpes Simplex Viruses. Journal of Pure & Applied Microbiology, 8, 155-159. |
[61] | Dkhil, M.A. (2014) Role of Berberine in Ameliorating Schistosoma Mansoni-Induced Hepatic Injury in Mice. Biological Research, 47, 1-7. |
[62] | Wu, Y., Li, J.Q., Kim, Y.J., et al. (2011) In Vivo and in Vitro Antiviral Effects of Berberine on Influenza Virus. Chinese Journal of Integrative Medicine, 17,444-452. https://doi.org/10.1007/s11655-011-0640-3 |
[63] | Shin, H.B., Choi, M.S., Yi, C.M., et al. (2015) Inhibition of Respiratory Syncytial Virus Replication and Virus-Induced p38 Kinase Activity by Berberine. International Im-munopharmacology, 27, 65-68.
https://doi.org/10.1016/j.intimp.2015.04.045 |
[64] | Kwon, M., Choi, Y.A., Choi, M.K., et al. (2015) Organic Cation Transporter-Mediated Drug-Drug Interaction Potential between Berberine and Metformin. Archives of Pharmacal Research, 38, 849-856.
https://doi.org/10.1007/s12272-014-0510-6 |
[65] | Zhou, Y., He, P., Liu, A., et al. (2012) Drug-Drug Interactions between Ketoconazole and Berberine in Rats: Pharmacokinetic Effects Benefit Pharmacodynamic Synergism. Phyto-therapy Research, 26,772-777.
https://doi.org/10.1002/ptr.3621 |
[66] | 佟树敏, 李学静, 杨先芹. 0.6%苦?小檗碱杀菌水剂研制及在苹果树上的应用[J]. 农业环境科学学报, 2002, 21(1): 67-69. |
[67] | 余占海, 张国英, 张小恒, 等. 盐酸小檗碱对体外培养人牙周膜细胞生物活性的影响[J]. 实用口腔医学杂志, 2007, 23(5): 637-640. |