Preparation, Characterization and Antimicrobial Studies of Mn(II) and Fe(II) Complexes with Schiff Base Ligand Derived from 2-aminophenol and 3-formyl-2-hydroxy-6-methoxyquinoline
Schiff
base derived from 2-aminophenol and 3-formyl-2-hydroxy-6-methoxyquinoline and
its Mn(II) and Fe(II) complexes were synthesized and characterized by melting
point and decomposition temperature, elemental analysis, molar conductivity, infrared
(IR) spectral analysis, atomic absorption spectroscopy (AAS) analysis,
solubility test, and magnetic susceptibility. The Fourier-transform infrared
spectroscopy (FTIR) spectral data of the Schiff base determined showed a band at 1622 cm−1 and this was
assigned to the v (C=N), which is a feature of azomethine group. The
same band was observed to shift to lower frequencies 1577 and 1599 cm−1 in the complexes suggesting coordination of the Schiff base with the respective
metal(II) ions. Molar conductance
values 14.58 and 12.65 Ω−1∙cm2∙mol−1 show that
the metal complexes were non-electrolyte in nature. The magnetic susceptibility
of the complexes was determined and the gram magnetic susceptibility of the
complexes was found to be positive, revealing that they are paramagnetic. The
elemental analysis of the complexes
References
[1]
Aliyu, H.N. (2018) Schiff Bases and Their Metal Complexes: The Drugs for the Next Generation. Professorial Inaugural Lecture Series. Bayero University, Kano, Nigeria.
[2]
Yahyazadeh, A. and Azimi, V. (2013) Synthesis of Some Unsymmetrical New Schiff. European Chemical Bulletin, 2, 453-455.
[3]
Chaudary, N.K. (2012) Synthesis and Medicinal Use of Metal Complexes of Schiff Bases. BIBECHANA, 9, 72-80. https://doi.org/10.3126/bibechana.v9i0.7178
[4]
Zoubi, W.A. (2013) Biological Activities of Schiff Bases and Their Complexes: A Review of Recent Works. International Journal of Organic Chemistry, 3, 73-95. https://doi.org/10.4236/ijoc.2013.33A008
[5]
Arulmurugan, S., Kavitha, H.P. and Venkatraman, B.R. (2010) Biological Activities of Schiff Base and Its Complexes: A Review. Rasayan Journal of Chemistry, 3, 385-410.
[6]
Emriye, A.Y. (2016) Synthesis and Characterization of Schiff Base. 1-Amino-4-Methylpiperazine Derivatives. CBU Journal of Sciences, 12, 375-392.
[7]
Savithri, K. and Revanasiddappa, H.D. (2018) Synthesis and Characterization of Oxidovanadium (IV) Complexes of 2-((E)-(6Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Binding Studies. Bioinorganic Chemistry and Applications, 2018, Article ID: 2452869. https://doi.org/10.1155/2018/2452869
[8]
Qin, W., Long S., Panunzio, M. and Biondi, S. (2013) Schiff Bases: A Short Survey on an Evergreen Chemistry Tool. Molecules, 18, 12264-12289. https://doi.org/10.3390/molecules181012264
[9]
Wang, L., Wang, Y., Hou, Z. and Liu, Y. (2012) Synthesis and Fluorescence Property of Novel Zn2+ Schiff Base Complex. Advanced Materials Research, 535-537, 1237-1240. https://doi.org/10.4028/www.scientific.net/AMR.535-537.1237
[10]
Ashraf, M.A. Mahmood, A. and Wajid, A. (2017) Synthesis, Characterization and Biological Actibity of Schiff Bases. International Conference on Chemistry and Chemical Process, 4, 25-37.
[11]
Jorgensen, J.H. and Turnidge, J.D. (2003) Susceptibility Test Methods: Dilution and Disk Diffution Methods. Manual of Clinical Microbiology. 8th Edition, American Society of Microbiology, Washington DC, 1108-1127.
[12]
Eman, T.S. (2015) Synthesis, Characterization and Spectroscopic Studies of 2-{{E}-Hydroxyphenyl) imino) methyl} Phenol Schiff Base with Some Metal Complexes. Journal of Al-Nahrain University, 18, 39-45. https://doi.org/10.22401/JNUS.18.1.05
[13]
Abubakar, A.A., Yusuf, Y. and Hussaini, A.U. (2017) Synthesis and Characterization of Cu(II) and Zn(II) Schiff Base Complexes. International Journal of Science and Applied Research, 2, 8-16.
[14]
Abdullahi, O.S. and Gareth, M.W. (2013) Antimicrobial activity and Cu(II) Complexes of Schiff Bases Derived from Orthoaminophenol and Salicylaldehyde Derivatives. Journal of Chemical and Pharmaceutical Research, 5, 147-154.
[15]
Siddappa, K. and Reddy, P.C. (2012) Siddappa, Synthesis, Spectral Characterization and Antimicrovial Studies of Transition Metal(II) Complexes with Schiff Base 3-[92-hydroxy-6-methoxyquinoline3-ylmethylene)-amino]-2-methyl-3H-quinoline-4-one. International Journal of Applied Biology and Pharmaceutical Technology, 3, 168-176.
[16]
El-ajaily, M.M., Maihub, A.A., Hudere, S.S. and Ben Saber, S.M. (2006) Nickel(II) Chelate of Schiff Base Derived from 4-Dimethylaminobenzaldehyde with Cysteine. Asian Journal of Chemistry, 18, 2427-2430.
[17]
Mounika, K., Anupama, B., Pragathi, J. and Gyanakumari, C. (2010) Synthesis, Characterization and Biological Activity of a Schiff Base Derived from 3-Ethoxy Salicyladehyde and 2-Amino Benzoic Acid and Its Transition Metal Complexes. Journal of Scientific Research, 2, 513-524. https://doi.org/10.3329/jsr.v2i3.4899
[18]
Rasha, S.J. and Farah, M.I. (2012) Synthesis and Characterization of Tetradentate Bissalicylaldehyde Schiff Base with Some Transition Metal Complexes. The First Scientific Conference of the College of Education for Pure Sciences, AL-Nahrain University, 25-26 April 2020, 124-131.
