A Bit Exagerrated Role of Complete Blood Count Parameters On the Prognosis of Idiopathic Sudden Sensorineural Hearing Loss - A Bit Exagerrated Role of Complete Blood Count Parameters On the Prognosis of Idiopathic Sudden Sensorineural Hearing Loss - Open Access Pub

Idiopathic sudden sensorineural hearing loss (ISSHL) is a commonly seen otorhinolaryngology emergency, and its etiology is still a mystery. In this retrospective clinical study, we aimed to investigate the possible relationship of inflammatory markers derived from CBC such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), Red cell distribution width-to-platelet ratio (RPR), lymphocyte-to-monocyte ratio (LMR), mean platelet volume (MPV) and platelet distribution width (PDW) in ISSHL . A total of 50 idiopathic sudden hearing loss patients were included in the study. They were grouped according to their hearing healing levels as recovered, partially recovered and unrecovered. Also 47 age- and sex- matched healthy individuals created the control group. Their complete blood count parameters of NLR, LMR, PLR, RPR, PDW and MPV were recorded. The results were statistically compared to bring out a significant difference between the groups. There was no significant demographic difference between the groups. The comparison of patient group with control group reveal a significant difference in the NLR, LMR and PDW values (p<0.05). The remaining values were not statistically significant. The analysis of these values according to the recovery level of the ISSHL, there was no statistical difference between the groups (p>0.05). We demonstrated for the first time that LMR value was significantly elevated in ISSHL patients. NLR, LMR, and PDW might be indicative for diagnosis of ISSHL. However, we believe that using these parameters for the screening of the prognosis is a clinically useless exercise. DOI10.14302/issn.2379-8572.joa-16-1366 Idiopathic sudden sensorineural hearing loss (ISSHL) is one of the emergency conditions of otorhinolaryngology (ORL), defined as 30 decibel (dB) or greater hearing loss at least three consecutive frequencies, occurring in less than 3 days with no identifiable etiology1. The incidence of ISSHL is 5 - 20 person per 100,000 individuals annually and accounts for 1% of all sensorineural hearing loss cases2. Although the existence of different treatment modalities, up to 65% of the cases recovers spontaneously without any treatment3. In current clinical practice, one of the most frequently ordered laboratory tests is the complete blood count (CBC). In this frequently ordered test, several parameters such as white blood cell, red blood cell and platelet counts and their ratios can be easily evaluated. In recent years, there have been many studies which assess the role of inflammatory and biochemical markers derived