Molluscicidal effect of sanguinarine against Oncomelania hupensis snails

A strong molluscicidal effect of sanguinarine against Oncomelania hupensis snails was demonstrated by immersion test in the present study. A positive relationship between doses, immersion time and the mortality of the snails was exhibited, while the optimal dose and immersion time of application towards the field eradication of snails were suggested. The possible mechanisms of effects were explored by determining the changes in liver aminotransferases (ALT, AST) of the snails and it was revealed that the damage of liver cells was the cause of snail death