Mixed Adenosquamous Histology is Associated with Poorer Survival of Cervical Cancer Stage 1b

All women with lymph node metastasis were discussed with the oncologist (Table 1). Only half of the women with lymph node metastasis received adjuvant treatment; nine had radiotherapy, one chemotherapy, and thirteen chemotherapy as well as radiotherapy. Survival was associated with presence of lymph node metastasis (Χ2 = 13, p<0.001) with a 5 years survival of 70 % (50-90 %, n = 24) and 93 % (89.4-96.5 %, n = 117) for lymph node positive and negative cervical cancer, respectively. Histological evaluation showed that adenosquamous cervical cancer was associated with poorer survival than the pure squamous and adenocarcinoma type (Figure 1). Five years survival rate was 40 % (2-78 %, n = 7) for mixed type and 92 % (87-97 %, n = 90) for pure type. The adenosquamous type was associated with lymph node metastasis (OR = 5.6 (1.8, 17.4), Fischer’s Exact test, p<0.02) but not with size of tumor, involvement of vagina, parametrium, and lymph vessels. Similarly, adjuvant treatment was associated with presence of lymph node metastasis (OR = 10.7 (3.8, 30), p<0.001) and the survival with adjuvant treatment tended to be lower (p<0.09, Log-rank test) which was associated with lymph node involvement