Angioleiomyoma of Nasal Septum: Case Report and Literature Review SciDoc Publishers | Open Access | Science Journals | Media Partners

The patient was taken to the operating room for endoscopic resection. The mass was observed to extend to the superior aspect of the internal nasal valve without involvement of the upper lateral nasal cartilage. The mass was removed en bloc including a wide cuff of normal mucosa circumferentially around the mass before dissecting the mass from the nasal septal cartilage, preserving perichondrium, without disrupting the nasal valve, upper lateral cartilage, or right nasal ala. No septal perforation was noted intraoperatively or at 3 months post operatively. The specimen was sent for permanent pathology. The gross specimen was 3.0 x 2.0 x 1.2 cm in size and tan and pink in appearance with a smooth and glistening surface. H&E stain revealed a well-circumscribed tumor with proliferation of fascicles of smooth muscle cells and surrounding thick-walled vessels with narrow lumens (Figure 3). The endothelial cells lacked pleomorphism, mitosis, nuclear atypia, or necrosis. Immunohistochemistry was positive for SMA, which revealed the smooth muscle cell component, as well as ERG1 (nuclear stain), which highlighted the endothelial cells lining narrow vessel lumens (Figure 4)