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The aim of this study was to present a case report of surgical removal of hyperplasia in the oral cavity using diode laser radiation and rehabilitation with a complete denture. Epulis fissuratum is a pseudotumor growth located over the soft tissue of the vestibular sulcus caused by the chronic irritation from the poorly adapted dentures. The case discussed in the present study reported with the massive fibrous mass (5x2x1 cm) with multiple folds located in the maxillary vestibular sulcus extending bilaterally from canine to canine region. This massive lesion was excised using diode laser and new complete dentures with proper peripheral extensions were fabricated and delivered to the patient. Patient was kept on regular follow up and clinical examination revealed normal vestibular mucosa and functionally sufficient prosthesis