Patent ductus arteriosus and pulmonary artery aneurism in a child affected by Loeys-Dietz syndrome | Cardiogenetics

We report the case of a 3-year old girl affected by Loeys-Dietz syndrome, a rare association of aneurysms and tortuosity of arteries associated to hypertelorism and cleft palate that was firstly described by Loeys and Dietz in 2005. The patient developed aneurysms of aortic root and of pulmonary artery, besides a patent ductus arteriosus was evidenced. We also reviewed the current literature concerning the aetiology and management of this syndrome