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-  2018 

Changes in energy metabolism, and levels of stress-related hormones and electrolytes in horses after intravenous administration of romifidine and the peripheral α-2 adrenoceptor antagonist vatinoxan

DOI: 10.1186/s13028-018-0380-x

Keywords: α-2 adrenoceptor agonist, Glucose, Horse, Hyperglycaemia, Insulin, MK-467, Romifidine, Vatinoxan

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Abstract:

Mean plasma glucose concentration of seven horses. The horses received romifidine (ROM, 80 μg/kg IV), ROM with vatinoxan (ROM?+?V, 80 μg/kg?+?200 μg/kg IV) and vatinoxan (V, 200 μg/kg IV) at T0. Error bars indicate the standard deviation. Plasma glucose concentrations were significantly different (P?<?0.05) from baseline at T60 and T120 after ROM and at T30, T60 and T120 after ROM?+?V. Significant difference (P?<?0.05) between * ROM and ROM?+?V, ?ROM?+?V and V and ?ROM and

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