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- 2019
Novel Gliclazide Electrosprayed Nano-Solid Dispersions: Physicochemical Characterization and Dissolution EvaluationKeywords: Amorphous solid dispersions, Eudragit? RS100, Electrospray, Gliclazide, In vitro evaluation, Nanocrystalline, Polyethylene glycol 6000 Abstract: Purpose: In the current study, electrospraying was directed as a novel alternative approach to improve the physicochemical attributes of gliclazide (GLC), as a poorly water-soluble drug, by creating nanocrystalline/amorphous solid dispersions (ESSs)
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