Literature Review for Office-Based Anesthesia

This study analyzed the impact of liposomal bupivacaine (regardless of administration route) on inpatient opioid use, resource utilization, and opioid-related complications among patients undergoing knee arthroplasty with a peripheral nerve block. A total of 88,830 surgeries from the Premier Healthcare Database were examined. Liposomal bupivacaine was used in 18,817 of these surgeries (21.2%). No association was found between the use of liposomal bupivacaine and clinically meaningful reduction in inpatient opioid use, opioid-related complications, or resource outcomes