The Assessment of Serum Apelin-12 Level in a Variety of Pulmonary Malignancies in Smokers

Apelin has recently been considered as an adipokine secreted from visceral fat. Apelin and its receptor exist in many tissues including lung and play significant roles in many physiological and pathological activities. However, serum level of apelin-12 is unknown in smokers and in various types of lung malignancies. Therefore, the amount of this hormone in non-patient smokers and the correlation of apelin serum level with the types of lung cancer in smokers afflicted with lung cancer are evaluated in this study