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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

Retinal ganglion cell–inner plexiform layer thickness is nonlinearly associated with cognitive impairment in the community-dwelling elderly

DOI: 10.1016/j.dadm.2018.10.006

Keywords: Retina, Alzheimer's disease, Biomarkers, Preclinical AD, Cognitive impairment, Optical coherence tomography, OCT, Ganglion cell–inner plexiform layer, GC-IPL, Retinal nerve fiber layer, RNFL, Retinal ganglion cell, Amyloid hypothesis, Synaptic dysfunction, Dendritic pathology

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Abstract:

Thinning of optical coherence tomography–measured retinal nerve fiber layer thickness and ganglion cell–inner plexiform layer (GC-IPL) thickness has been found in patients with Alzheimer's disease. However, the association of these retinal markers and cognition in nondemented elders may not be linear

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