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- 2019
Factors affecting the harmonization of disease-related metabolic brain pattern expression quantification in [18F]FDG-PET (PETMETPAT)DOI: 10.1016/j.dadm.2019.04.002 Keywords: Neuroimaging biomarker, FDG-PET, Harmonization, Hoffman 3D brain phantom, Principal component analysis Abstract: The implementation of spatial-covariance [18F]fluorodeoxyglucose positron emission tomography–based disease-related metabolic brain patterns as biomarkers has been hampered by intercenter imaging differences. Within the scope of the JPND-PETMETPAT working group, we illustrate the impact of these differences on Parkinson's disease–related pattern (PDRP) expression scores
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