Sample Size Calculation Guide - Part 3: How to Calculate the Sample Size for an Independent Case-control Study

In the previous educational articles, we explained how to calculate the sample size for a rate or a single proportion and how to calculate the sample size for an independent cohort study (1, 2). In this article, we will explain how to calculate the sample size for an independent case-control study based on the odds ratios or two proportions representing the exposure rates in the case and the control groups