Images – Isolated forearm soft tissue metastasis from bladder cancer

Bladder cancer is the ninth most prevalent cancer in the world and most common malignancy involving the urinary system, with 430 000 cases diagnosed in 2012.1 Urothelial cell carcinoma (UCC, also known as transitional cell carcinoma) is considered to be the predominant histological type of bladder cancer in the U.S. and Western Europe. While greater than 50% of UCC cases are non-muscle-invasive with relatively good prognosis, soft tissue invasion and metastatic spread offer much worse outcomes.2 The most common areas for metastatic spread of UCC are the lymph nodes, bones, lung, and liver. Advanced UCC has a poor prognosis, with an overall five-year survival of less than 15%.