Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner

DOI: 10.1186/s40170-018-0178-3

Keywords: IDH1 mutation, 2-Hydroxyglutarate, Metabolic reprogramming, Magnetic resonance spectroscopy, Phosphocholine, Phosphoethanolamine, Choline kinase, Ethanolamine kinase, HIF-1α, Brain tumors

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