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- 2019
Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignanciesDOI: 10.1002/cam4.1844 Keywords: eosinophilic granuloma, histiocytosis, Langerhans, Langerhans cell histiocytosis, second malignancies Abstract: Langerhans cell histiocytosis (LCH) is a rare disorder of histiocyte proliferation. Previous case studies suggest a higher prevalence of hematologic and solid malignancies among LCH patients, possibly due to treatment with tumorigenic agents such as etoposide. We report the first large, single‐institution experience of adult LCH patients with additional malignancies to study the characteristics of these patients
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