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- 2017
Biomarker driven treatment of head and neck squamous cell cancerDOI: 10.1186/s41199-017-0025-1 Keywords: Head and neck squamous cell cancer (HNSCC), Biomarkers, Human papilloma virus (HPV), Epidermal growth factor receptor (EGFR), Epstein Barr virus (EBV), Cetuximab, Nasopharyngeal carcinoma (NPC), Phosphatase and tensin homolog (PTEN), Phosphoinositide 3- kinase (PI3K) Abstract: EGFR and receptor tyrosine kinase signaling in head and neck cancer. Resistance to EGFR inhibition may arise via signaling from redundant tyrosine kinases, such as HER family members, as well as downstream signaling activation. These may be important biomarkers predicting therapeutic response in head and neck cance
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