|
- 2019
XPD suppresses cell proliferation and migration via miR-29a-3p-Mdm2/PDGF-B axis in HCCDOI: 10.1186/s13578-018-0269-4 Keywords: XPD, MiR-29a-3p, Cell proliferation and migration, Hepatocellular carcinoma Abstract: The expression of XPD and miR-29a-3p was downregulated in HCC. a, b Western blot and qRT-PCR analysis of XPD expression in HCC tissue samples and their corresponding adjacent non-tumorous liver samples. (n?=?68). (*P?<?0.05, vs. non-tumor). c QRT-PCR analysis of miR-29a-3p expression in HCC tissue samples and their corresponding adjacent non-tumorous liver samples. (n?=?68). (*P?<?0.05, vs. non-tumor). d Correlation analysis of miR-29a-3p and XPD expression HCC tissue samples. (n?=?68). e, f Western blot and qRT-PCR analysis of XPD expression in normal human hepatic cell line (LO2) and HCC cells lines (HepG2, SMMC-7721, Hep3B). (*P?<?0.05, vs. LO2). g QRT-PCR analysis of miR-29a-3p expression in normal human hepatic cell line (LO2) and HCC cells lines (HepG2, SMMC-7721, Hep3B). (*P?<?0.05, vs. LO2
|