LncRNA MALAT1 promotes osteoarthritis by modulating miR-150-5p/AKT3 axis

Different expression levels of MALAT1, miR-150-5p and AKT3 in normal and OA cartilage chondrocytes. a, b The expression levels of MALAT1, miR-150-5p and AKT3 in OA and normal cartilage tissues were detected by qRT-PCR and western blot. Samples were from 42 OA patients and 20 healthy subscribers. c Spearman was used to analyze the relationship between MALAT1, miR-150-5p and AKT3. d, e qRT-PCR and western blot were used to examine the levels of MALAT1, miR-150-5p and AKT3 in chondrocytes with treatment of 10 ng/mL IL-1β for 4, 6, 12, and 24 h. *P？<？0.0