Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling

DOI: 10.1186/s12964-019-0356-0

Keywords: Inflammation, Signal transduction, Interleukin-6, IL-6, Classic signalling, Trans-signalling, Jak/STAT signalling, IL-6 receptor α, gp130, Systems biology, Computational dynamic modelling, Set-based modelling and analysis

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