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- 2019
ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1DOI: 10.1080/15384047.2018.1507256 Keywords: Oncogenic signalling, epithelial-mesenchymal transition, Wnt signalling, RNA-seq, protein networks Abstract: Background: Epithelial-to-mesenchymal transition (EMT) is a key step in the transformation of epithelial cells into migratory and invasive tumour cells. Intricate positive and negative regulatory processes regulate EMT. Many oncogenic signalling pathways can induce EMT, but the specific mechanisms of how this occurs, and how this process is controlled are not fully understood
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