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-  2019 

Study of Telomere Length in Preimplanted Cultured Chondrocytes

DOI: 10.1177/1947603517749918

Keywords: telomere length, telomerase, high-density autologous chondrocyte implantation, quantitative fluorescent in situ hybridization

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Abstract:

In the process of cell division, the extremes of the eukaryotic chromosomes are progressively shortening, and this phenomenon is related to cell degeneration and senescence. The treatment of cartilage lesions with autologous chondrocytes implies that cells proliferate in an artificial environment. We have studied the viability of cultured chondrocytes after measurement of their telomere length before implantation

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