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- 2019
Study of Telomere Length in Preimplanted Cultured ChondrocytesKeywords: telomere length, telomerase, high-density autologous chondrocyte implantation, quantitative fluorescent in situ hybridization Abstract: In the process of cell division, the extremes of the eukaryotic chromosomes are progressively shortening, and this phenomenon is related to cell degeneration and senescence. The treatment of cartilage lesions with autologous chondrocytes implies that cells proliferate in an artificial environment. We have studied the viability of cultured chondrocytes after measurement of their telomere length before implantation
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