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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

In Vitro Analysis of the Differentiation Capacity of Postmortally Isolated Human Chondrocytes Influenced by Different Growth Factors and Oxygen Levels

DOI: 10.1177/1947603517719318

Keywords: cartilage, chondrocytes, 3D pellet cultures, growth factors, oxygen, chondrogenic differentiation

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Abstract:

In the present in vitro study, we analyzed the chondrogenic differentiation capacity of human chondrocytes postmortally isolated from unaffected knee cartilage by the addition of transforming growth factor–β1 (TGF-β1) and/or insulin-like growth factor–1 (IGF-1) and different oxygen levels

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