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-  2019 

CXCR4 knockdown prevents inflammatory cytokine expression in macrophages by suppressing activation of MAPK and NF-κB signaling pathways

DOI: 10.1186/s13578-019-0315-x

Keywords: CXCR4, IL-6, TNF-α, Macrophage, MAPK, NF-κB

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Abstract:

The expression of CXCR4 was detected in ALI lung tissue and alveolar macrophages. a Immunofluorescence analyzed a number of macrophages in ALI lung tissue. b Immunofluorescence analyzed the expression of CXCR4 in ALI lung tissue. c RT-qPCR analyzed CXCR4 expression in alveolar macrophages. CXCR4 in macrophage of lung tissue in control group (×200) and ALI group (×200). Data shown represent at least three independent experiments. *p?<?0.05, **p?<?0.01, and ***p?<?0.001 compared with control group. Error bars represent S

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