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-  2016 

Mitochondria-cytoskeleton associations in mammalian cytokinesis

DOI: 10.1186/s13008-016-0015-4

Keywords: Mitochondria, Cytoskeleton, Cytokinesis, Microtubules, Actin, Miro, KIF5B

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Abstract:

The role of the cytoskeleton in regulating mitochondrial distribution in dividing mammalian cells is poorly understood. We previously demonstrated that mitochondria are transported to the cleavage furrow during cytokinesis in a microtubule-dependent manner. However, the exact subset of spindle microtubules and molecular machinery involved remains unknown

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